Repository details
Follicular Lymphoma Genome Data at Canada's Michael Smith Genome Sciences Centre (BCGSC)
Name of repository
Follicular Lymphoma Genome Data at Canada's Michael Smith Genome Sciences Centre (BCGSC)
Repository URL
Subject(s)
Description
<<<!!!<<< Genome data generated by BC Genome Sciences Centre is no longer available through this site as it is regularly deposited into controlled data repositories such as the European Genome Phenome Archive (EGA); ICGC (International Cancer Genome Consortium) and the Genome Data Commons (GDC) >>>!!!>>>
Mapping, copy number analysis, sequence and gene expression data generated by the High Resolution Analysis of Follicular Lymphoma Genomes project. The data will be available for 24 patients with follicular lymphoma. All data will be made as widely and freely available as possible while safeguarding the privacy of participants, and protecting confidential and proprietary data.The data from this project will be submitted to public genomic data sources. These sources will be listed on this web site as the data becomes available in these external data sources.
Contact
- info@bcgsc.ca
Content type(s)
Keyword(s)
Repository type(s)
- disciplinary
- institutional
Research data repository language(s)
- English
Data and/or service provider
- data provider
Institution name
Country
Type(s) of responsibility
- funding
Type of institution
non-profit
Institution name
Additional name(s)
- BC Cancer Agency, Research Centre
- BCGSC
Country
Type(s) of responsibility
- general
- technical
Type of institution
non-profit
Institution name
Additional name(s)
- BCGSC
Contact(s)
- jschein@bcgsc.ca
Country
Type(s) of responsibility
- general
Type of institution
non-profit
Policies (1)
Policy Name
Database access
Type of access to research data repository
open
Data access (1)
Type of access to data
open
Data licenses (2)
Data upload (1)
Type of data upload
restricted
Data upload restriction type(s)
- registration
Persistent identifier system(s)
- none
Name of the repository software
- unknown
Data citation guideline
Enhanced Publication
unknown
Quality management
unknown
Remarks
Remarks
Follicular lymphoma (FL), the most common type of lymphoma, is a cancer of the cells of the immune system. Follicular lymphoma is associated with a specific genome rearrangement where parts of chromosomes 14 and 18 have exchanged. This rearrangement is an initiating event for FL but insufficient without additional mutation events for cancer development. Furthermore, there may be more genome rearrangements to progress from FL to a more aggressive form of the disease, diffuse large B-cell lymphoma. To understand the relationship between rearrangements and disease, this project will identify rearrangements in the FL genome and then analyze the rearrangements to determine their effect on gene structure. Because this is one of the first in depth genome profiling of human cancers, recurrent genomic rearrangements will advance knowledge not only about lymphoma but about cancer in general. Understanding the dysfunctions in lymphoma will permit researchers to develop new diagnostic and prognostic markers and possibly new therapies.
Entry date
2014-02-20
Last update
2022-06-08
Cite this re3data.org record:
re3data.org: Follicular Lymphoma Genome Data at Canada's Michael Smith Genome Sciences Centre (BCGSC); editing status 2022-06-08; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R3KC8W last accessed: 2024-04-25- Current projects
- EOSC FAIR-IMPACT
- re3data COREF
-
To the extent possible under law,
re3data.org
has waived all copyright and related or neighboring rights to
the database entries of re3data.org.
-
Except where otherwise noted, content on this site is licensed under a
Creative Commons Attribution 4.0 International License
.
- Cite this service: re3data.org - Registry of Research Data Repositories. https://doi.org/10.17616/R3D last accessed: 2024-04-25
