Repository details
International Mouse Phenotyping Consortium
Name of repository
International Mouse Phenotyping Consortium
Additional name(s)
- IMPC
- The International Knockout Mouse Consortium
- IKMC
- Intgernational Mouse Phenotyping Consortium
Repository URL
Subject(s)
Description
The IMPC is a confederation of international mouse phenotyping projects working towards the agreed goals of the consortium: To undertake the phenotyping of 20,000 mouse mutants over a ten year period, providing the first functional annotation of a mammalian genome. Maintain and expand a world-wide consortium of institutions with capacity and expertise to produce germ line transmission of targeted knockout mutations in embryonic stem cells for 20,000 known and predicted mouse genes.
Test each mutant mouse line through a broad based primary phenotyping pipeline in all the major adult organ systems and most areas of major human disease.
Through this activity and employing data annotation tools, systematically aim to discover and ascribe biological function to each gene, driving new ideas and underpinning future research into biological systems;
Maintain and expand collaborative “networks” with specialist phenotyping consortia or laboratories, providing standardized secondary level phenotyping that enriches the primary dataset, and end-user, project specific tertiary level phenotyping that adds value to the mammalian gene functional annotation and fosters hypothesis driven research; and
Provide a centralized data centre and portal for free, unrestricted access to primary and secondary data by the scientific community, promoting sharing of data, genotype-phenotype annotation, standard operating protocols, and the development of open source data analysis tools.
Members of the IMPC may include research centers, funding organizations and corporations.
Content type(s)
Persistent identifier(s) of the repository
- RRID:nlx_151660
- RRID:SCR_006158
- FAIRsharing_DOI:10.25504/FAIRsharing.LdoU1I
Repository size
8.707 phenotyped genes; 9.393 phenotyped mutant lines; 104.530 phenotype calls;
Repository type(s)
- disciplinary
Mission statement for designated community
Research data repository language(s)
- English
Data and/or service provider
- data provider
Institution name
Additional name(s)
- APN
Identifier(s)
- RRID:SCR_006150
- RRID:nlx_151641
- ROR:0201hm243
Country
Type(s) of responsibility
- general
Type of institution
non-profit
Institution name
Identifier(s)
- ROR:02pttbw34
Contact(s)
Country
Type(s) of responsibility
- general
Type of institution
non-profit
Additional name(s)
- CNR Monterotondo
- EMMA (European Mouse Mutant Archive)
Country
Type(s) of responsibility
- general
Type of institution
non-profit
Additional name(s)
- EMBL-EBI
Identifier(s)
- RRID:SCR_004727
- RRID:nlx_72386
- ROR:02catss52
Country
Type(s) of responsibility
- general
Type of institution
non-profit
Identifier(s)
- RRID:SCR_013835
- ROR:00cfam450
Country
Type(s) of responsibility
- general
Type of institution
non-profit
Institution name
Additional name(s)
- ICS
Identifier(s)
- RRID:SCR_011021
- RRID:nlx_158126
- ROR:03cjqqq10
Country
Type(s) of responsibility
- general
Type of institution
non-profit
Institution name
Additional name(s)
- IMPC
Identifier(s)
- RRID:SCR_006158
Contact(s)
Country
Type(s) of responsibility
- general
- technical
Type of institution
non-profit
Institution name
Additional name(s)
- Model Animal Research Center of Nanjing University
Country
Type(s) of responsibility
- general
Type of institution
non-profit
Institution name
Additional name(s)
- MRC Mouse Network
Identifier(s)
- ROR:0001h1y25
- RRID:SCR_008013
Country
Type(s) of responsibility
- general
Type of institution
non-profit
Additional name(s)
- NLAC, NARLabs
Identifier(s)
- ROR:05wcstg80
Country
Type(s) of responsibility
- general
Type of institution
non-profit
Institution name
Additional name(s)
- RIKEN BRC
Identifier(s)
- RRID:SCR_003250
- RRID:nif-0000-31407
- ROR:00s05em53
Country
Type(s) of responsibility
- general
Type of institution
non-profit
Institution name
Contact(s)
- snumouse@snu.ac.kr
Country
Type(s) of responsibility
- general
Type of institution
non-profit
Institution name
Additional name(s)
- TCP
Identifier(s)
- RRID:SCR_006143
- RRID:nlx_151633
- ROR:044xrc068
Contact(s)
Country
Type(s) of responsibility
- general
Type of institution
non-profit
Institution name
Additional name(s)
- DTCC Consortium
Contact(s)
Country
Type(s) of responsibility
- general
Type of institution
non-profit
Institution name
Additional name(s)
- JAX
Identifier(s)
- RRID:SCR_004633
- RRID:nlx_63162
- RRID:SciEx_9305
- ROR:021sy4w91
Contact(s)
Country
Type(s) of responsibility
- general
Type of institution
non-profit
Institution name
Identifier(s)
- RRID:SCR_011784
- RRID:nlx_91258
- ROR:05cy4wa09
Country
Type(s) of responsibility
- general
Type of institution
non-profit
Policies (2)
Policy Name
Policy Name
Database access
Type of access to research data repository
open
Database licenses (1)
Database License
Data access (1)
Type of access to data
open
Data licenses (1)
DataLicense
Data upload (1)
Type of data upload
restricted
Data upload restriction type(s)
- other
Persistent identifier system(s)
- none
Name of the repository software
- unknown
Versioning
yes
Data citation guideline
Enhanced Publication
yes
Quality management
yes
Application programming interfaces (2)
Remarks
Remarks
The web services of the International Knockout Mouse (IKMC) have been transferred to the International Mouse Phenotyping Consortium (IMPC). The International Mouse Phenotyping Consortium (IMPC) Comprises a group of major mouse genetics research institutions along with national funding organisations formed to address the challenge of developing an encyclopedia of mammalian gene function. The IMPC is currently composed of 18 research institutions and 5 national funders https://www.mousephenotype.org/about-impc/consortium-members/
The IKMC includes the following programs: Knockout Mouse Project (KOMP) (USA),European Conditional Mouse Mutagenesis Program (EUCOMM) (Europe), EUCOMM: Tools for Functional Annotation of the Mouse Genome (EUCOMMTOOLS) (Europe), North American Conditional Mouse Mutagenesis Project (NorCOMM) (Canada), Texas A&M Institute for Genomic Medicine (TIGM) (USA)
Entry date
2014-03-06
Last update
2024-03-15
Cite this re3data.org record:
re3data.org: International Mouse Phenotyping Consortium; editing status 2024-03-15; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R3QW4S last accessed: 2024-04-20- Current projects
- EOSC FAIR-IMPACT
- re3data COREF
-
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- Cite this service: re3data.org - Registry of Research Data Repositories. https://doi.org/10.17616/R3D last accessed: 2024-04-20
