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Found 16 result(s)
The Structure database provides three-dimensional structures of macromolecules for a variety of research purposes and allows the user to retrieve structures for specific molecule types as well as structures for genes and proteins of interest. Three main databases comprise Structure-The Molecular Modeling Database; Conserved Domains and Protein Classification; and the BioSystems Database. Structure also links to the PubChem databases to connect biological activity data to the macromolecular structures. Users can locate structural templates for proteins and interactively view structures and sequence data to closely examine sequence-structure relationships.
Pubchem contains 3 databases. 1. PubChem BioAssay: The PubChem BioAssay Database contains bioactivity screens of chemical substances described in PubChem Substance. It provides searchable descriptions of each bioassay, including descriptions of the conditions and readouts specific to that screening procedure. 2. PubChem Compound: The PubChem Compound Database contains validated chemical depiction information provided to describe substances in PubChem Substance. Structures stored within PubChem Compounds are pre-clustered and cross-referenced by identity and similarity groups. 3. PubChem Substance. The PubChem Substance Database contains descriptions of samples, from a variety of sources, and links to biological screening results that are available in PubChem BioAssay. If the chemical contents of a sample are known, the description includes links to PubChem Compound.
A place where researchers can publicly store and share unthresholded statistical maps, parcellations, and atlases produced by MRI and PET studies.
The Saccharomyces Genome Database (SGD) provides comprehensive integrated biological information for the budding yeast Saccharomyces cerevisiae along with search and analysis tools to explore these data, enabling the discovery of functional relationships between sequence and gene products in fungi and higher organisms.
>>>>!!!!<<<< The Cancer Genomics Hub mission is now completed. The Cancer Genomics Hub was established in August 2011 to provide a repository to The Cancer Genome Atlas, the childhood cancer initiative Therapeutically Applicable Research to Generate Effective Treatments and the Cancer Genome Characterization Initiative. CGHub rapidly grew to be the largest database of cancer genomes in the world, storing more than 2.5 petabytes of data and serving downloads of nearly 3 petabytes per month. As the central repository for the foundational genome files, CGHub streamlined team science efforts as data became as easy to obtain as downloading from a hard drive. The convenient access to Big Data, and the collaborations that CGHub made possible, are now essential to cancer research. That work continues at the NCI's Genomic Data Commons. All files previously stored at CGHub can be found there. The Website for the Genomic Data Commons is here: https://gdc.nci.nih.gov/ >>>>!!!!<<<< The Cancer Genomics Hub (CGHub) is a secure repository for storing, cataloging, and accessing cancer genome sequences, alignments, and mutation information from the Cancer Genome Atlas (TCGA) consortium and related projects. Access to CGHub Data: All researchers using CGHub must meet the access and use criteria established by the National Institutes of Health (NIH) to ensure the privacy, security, and integrity of participant data. CGHub also hosts some publicly available data, in particular data from the Cancer Cell Line Encyclopedia. All metadata is publicly available and the catalog of metadata and associated BAMs can be explored using the CGHub Data Browser.
The NIDDK Information Network (dkNET) serves the needs of basic and clinical investigators by providing seamless access to large pools of data and research resources relevant to the mission of The National Institute of Diabetes Digestive and Kidney Diseases (NIDDK).
The Argo observational network consists of a fleet of 3000+ profiling autonomous floats deployed by about a dozen teams worldwide. WHOI has built about 10% of the global fleet. The mission lifetime of each float is about 4 years. During a typical mission, each float reports a profile of the upper ocean every 10 days. The sensors onboard record fundamental physical properties of the ocean: temperature and conductivity (a measure of salinity) as a function of pressure. The depth range of the observed profile depends on the local stratification and the float's mechanical ability to adjust it's buoyancy. The majority of Argo floats report profiles between 1-2 km depth. At each surfacing, measurements of temperature and salinity are relayed back to shore via satellite. Telemetry is usually received every 10 days, but floats at high-latitudes which are iced-over accumulate their data and transmit the entire record the next time satellite contact is established. With current battery technology, the best performing floats last 6+ years and record over 200 profiles.
SESAR, the System for Earth Sample Registration, is a global registry for specimens (rocks, sediments, minerals, fossils, fluids, gas) and related sampling features from our natural environment. SESAR's objective is to overcome the problem of ambiguous sample naming in the Earth Sciences. SESAR maintains a database of sample records that are contributed by its users. Each sample that is registered with SESAR is assigned an International Geo Sample Number IGSN to ensure its global unique identification.
ArrayExpress is one of the major international repositories for high-throughput functional genomics data from both microarray and high-throughput sequencing studies, many of which are supported by peer-reviewed publications. Data sets are submitted directly to ArrayExpress and curated by a team of specialist biological curators. In the past (until 2018) datasets from the NCBI Gene Expression Omnibus database were imported on a weekly basis. Data is collected to MIAME and MINSEQE standards.
The Neuroscience Information Framework is a dynamic index of data, materials, and tools. Please note, we do not accept direct data deposits, but if you wish to make your data repository or database available through our search, please contact us. An initiative of the NIH Blueprint for Neuroscience Research, NIF advances neuroscience research by enabling discovery and access to public research data and tools worldwide through an open source, networked environment.
The MMRRC is the nation’s premier national public repository system for mutant mice. Funded by the NIH continuously since 1999, the MMRRC archives and distributes scientifically valuable spontaneous and induced mutant mouse strains and ES cell lines for use by the biomedical research community. The MMRRC consists of a national network of breeding and distribution repositories and an Informatics Coordination and Service Center located at 4 major academic centers across the nation. The MMRRC is committed to upholding the highest standards of experimental design and quality control to optimize the reproducibility of research studies using mutant mice.
The Astromaterials Data System (AstroMat) is a data infrastructure to store, curate, and provide access to laboratory data acquired on samples curated in the Astromaterials Collection of the Johnson Space Center. AstroMat is developed and operated at the Lamont-Doherty Earth Observatory of Columbia University and funded by NASA.
The World Register of Marine Species (WoRMS) integrates approximately 100 marine datbases to provide an authoritative and comprehensive list of marine organisms. WoRMS has an editorial system where taxonomic groups are managed by experts responsible for the quality of the information. WorMS register of marine species emerged from the European Register of Marine Species (ERMS) and the Flanders Marine Institute (VLIZ). WoRMS is a contribution to Lifewatch, Catalogue of Life, Encyclopedia of Life, Global Biodiversity Information Facility and the Census of Marine Life.
The CCHDO provides access to standard, well-described datasets from reference-quality repeat hydrography expeditions. It curates high quality full water column Conductivity-Temperature-Depth (CTD), hydrographic, carbon and tracer data from over 2,500 cruises from ~30 countries. It is the official data center for CTD and water sample profile data from the Global Ocean Ship-Based Hydrographic Investigations Program (GO-SHIP), as well as for WOCE, US Hydro, and other high quality repeat hydrography lines (e.g. SOCCOM, HOT, BATS, WOCE, CARINA.)
Brain Analysis Library of Spatial maps and Atlases (BALSA) is a database for hosting and sharing neuroimaging and neuroanatomical datasets for human and primate species. BALSA houses curated, user-created Study datasets, extensively analyzed neuroimaging data associated with published figures and Reference datasets mapped to brain atlas surfaces and volumes in human and nonhuman primates as a general resource (e.g., published cortical parcellations).
The Astrophysics Source Code Library (ASCL) is a free online registry for source codes of interest to astronomers and astrophysicists and lists codes that have been used in research that has appeared in, or been submitted to, peer-reviewed publications. The ASCL is citable by using the unique ascl ID assigned to each code. The ascl ID can be used to link to the code entry by prefacing the number with ascl.net (i.e., ascl.net/1201.001).