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STRING is a database of known and predicted protein interactions. The interactions include direct (physical) and indirect (functional) associations; they are derived from four sources: - Genomic Context - High-throughput Experiments - (Conserved) Coexpression - Previous Knowledge STRING quantitatively integrates interaction data from these sources for a large number of organisms, and transfers information between these organisms where applicable.
The European Space Agency's (ESA) X-ray Multi-Mirror Mission (XMM-Newton) was launched by an Ariane 504 on December 10th 1999. XMM-Newton is ESA's second cornerstone of the Horizon 2000 Science Programme. It carries 3 high throughput X-ray telescopes with an unprecedented effective area, and an optical monitor, the first flown on a X-ray observatory. The large collecting area and ability to make long uninterrupted exposures provide highly sensitive observations.
<<<!!!<<< Efforts to obtain renewed funding after 2008 were unfortunately not successful. PANDIT has therefore been frozen since November 2008, and its data are not updated since September 2005 when version 17.0 was released (corresponding to Pfam 17.0). The existing data and website remain available from these pages, and should remain stable and, we hope, useful. >>>!!!>>> PANDIT is a collection of multiple sequence alignments and phylogenetic trees. It contains corresponding amino acid and nucleotide sequence alignments, with trees inferred from each alignment. PANDIT is based on the Pfam database (Protein families database of alignments and HMMs), and includes the seed amino acid alignments of most families in the Pfam-A database. DNA sequences for as many members of each family as possible are extracted from the EMBL Nucleotide Sequence Database and aligned according to the amino acid alignment. PANDIT also contains a further copy of the amino acid alignments, restricted to the sequences for which DNA sequences were found.
The CERN Open Data portal is the access point to a growing range of data produced through the research performed at CERN. It disseminates the preserved output from various research activities, including accompanying software and documentation which is needed to understand and analyze the data being shared.
Herschel has been designed to observe the `cool universe'; it is observing the structure formation in the early universe, resolving the far infrared cosmic background, revealing cosmologically evolving AGN/starburst symbiosis and galaxy evolution at the epochs when most stars in the universe were formed, unveiling the physics and chemistry of the interstellar medium and its molecular clouds, the wombs of the stars, and unravelling the mechanisms governing the formation of and evolution of stars and their planetary systems, including our own solar system, putting it into context. In short, Herschel is opening a new window to study how the universe has evolved to become the universe we see today, and how our star the sun, our planet the earth, and we ourselves fit in.