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JASPAR is the leading open-access database of matrix profiles describing the DNA-binding patterns of transcription factors and other proteins interacting with DNA in a sequence-specific manner.
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Exposures in the period from conception to early childhood - including fetal growth, cell division, and organ functioning - may have long-lasting impact on health and disease susceptibility. To investigate these issues the Danish National Birth Cohort (Better health in generations) was established. A large cohort of pregnant women with long-term follow-up of the offspring was the obvious choice because many of the exposures of interest cannot be reconstructed with suffcient validity back in time. The study needed to be large, and the aim was to recruit 100,000 women early in pregnancy, and to continue follow-up for decades. Exposure information was collected by computer-assisted telephone interviews with the women twice during pregnancy and when their children were six and 18 months old. Participants were also asked to fill in a self-administered food frequency questionnaire in mid-pregnancy. Furthermore, a biological bank has been set up with blood taken from the mother twice during pregnancy and blood from theumbilical cord taken shortly after birth.
The International Service of Geomagnetic Indices (ISGI) is in charge of the elaboration and dissemination of geomagnetic indices, and of tables of remarkable magnetic events, based on the report of magnetic observatories distributed all over the planet, with the help of ISGI Collaborating Institutes. The interaction between the solar wind, including plasma and interplanetary magnetic field, and the Earth's magnetosphere results in a transfer of energy and particles inside the magnetosphere. Solar wind characteristics are highly variable, and they have actually a direct influence on the shape and size of the magnetosphere, on the amount of transferred energy, and on the way this energy is dissipated. It is clear that the great diversity of sources of magnetic variations give rise to a great complexity in ground magnetic signatures. Geomagnetic indices aim at describing the geomagnetic activity or some of its components. Each geomagnetic index is related to different phenomena occurring in the magnetosphere, ionosphere and deep in the Earth in its own unique way. The location of a measurement, the timing of the measurement and the way the index is calculated all affect the type of phenomenon the index relates to. The IAGA endorsed geomagnetic indices and lists of remarkable geomagnetic events constitute unique temporal and spatial coverage data series homogeneous since middle of 19th century.