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Found 47 result(s)
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A human interactome map. The sequencing of the human genome has provided a surprisingly small number of genes, indicating that the complex organization of life is not reflected in the gene number but, rather, in the gene products – that is, in the proteins. These macromolecules regulate the vast majority of cellular processes by their ability to communicate with each other and to assemble into larger functional units. Therefore, the systematic analysis of protein-protein interactions is fundamental for the understanding of protein function, cellular processes and, ultimately, the complexity of life. Moreover, interactome maps are particularly needed to link new proteins to disease pathways and the identification of novel drug targets.
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The project brings together national key players providing environmentally related biological data and services to develop the ‘German Federation for Biological Data' (GFBio). The overall goal is to provide a sustainable, service oriented, national data infrastructure facilitating data sharing and stimulating data intensive science in the fields of biological and environmental research.
The Satellite Application Facility on Climate Monitoring (CM SAF) develops, produces, archives and disseminates satellite-data-based products in support to climate monitoring. The product suite mainly covers parameters related to the energy & water cycle and addresses many of the Essential Climate Variables as defined by GCOS (GCOS 138). The CM SAF produces both Enviromental Data Records and Climate Data Records.
The Astrophysics Source Code Library (ASCL) is a free online registry for source codes of interest to astronomers and astrophysicists and lists codes that have been used in research that has appeared in, or been submitted to, peer-reviewed publications. The ASCL is citable by using the unique ascl ID assigned to each code. The ascl ID can be used to link to the code entry by prefacing the number with ascl.net (i.e., ascl.net/1201.001).
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The GeoPortal.rlp allows the central search and visualization of geo data. Inside the geo data infrastructure of Rhineland-Palatinate the GeoPortal.rlp inherit the central duty a service orientated branch exchange between user and offerer of geo data. The GeoPortal.rlp establishes the access to geo data over the electronic network. The GeoPortal.rlp was brought on line on January, 8th 2007 for the first time, on February, 2nd 2011 it occured a site-relaunch.
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HALO-DB is the web platform of a data retrieval and long-term archive system. The system was established to hold and to manage a wide range of data based on observations of the HALO research aircraft and data which are related to HALO observations. HALO (High-Altitude and LOng-range aircraft) is the new German research aircraft (German Science Community (DFG)). The aircraft, a Gulfstream GV-550 Business-Jet, is strongly modified for the application as a research platform. HALO offers several advantages for scientific campaigns, such as its high range of more than 10000 km, a high maximum altitude of more than 15 km, as well as a relatively high payload.
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Fordatis is the institutional research data repository of the Fraunhofer-Gesellschaft. Fraunhofer-Gesellschaft based in Germany is Europes largest research and technology organization. Fordatis contains research data created by researcher at Fraunhofer. These are data from the engineering, natural sciences and social sciences.
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The repository is no longer available <<<!!!<<< The Senate Commission on Oceanography planned and coordinated the activities of the DFG in the field of marine research from 1959 until 2017. Most notably, it advised on matters pertaining to the research vessels METEOR and (from 2006 onwards) MARIA S. MERIAN, which are co-funded by the DFG. The focus was on the review process and evaluation of proposed voyages for these two ships. The Expert Research Vessel Panel (GPF) appointed by the BMBF and DFG, which is responsible for the review process for proposed voyages for all global, oceanic and regional German research vessels within the framework of a joint procedure developed by the BMBF, DFG and HGF, was constituted on 7 March 2018 and thus took on this task concerning METEOR and MARIA S. MERIAN from the Senate Commission on Oceanography. More information on the new review process can be found on the German Research Vessels Portal. https://www.portal-forschungsschiffe.de/index.php?index=53 >>>!!!>>>
As with most biomedical databases, the first step is to identify relevant data from the research community. The Monarch Initiative is focused primarily on phenotype-related resources. We bring in data associated with those phenotypes so that our users can begin to make connections among other biological entities of interest. We import data from a variety of data sources. With many resources integrated into a single database, we can join across the various data sources to produce integrated views. We have started with the big players including ClinVar and OMIM, but are equally interested in boutique databases. You can learn more about the sources of data that populate our system from our data sources page https://monarchinitiative.org/about/sources.
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With Open Science OVGU the Otto-von-Guericke University provides its scientists with a research data repository. Measurement data, laboratory values, survey data, methodical test procedures, etc. can be archived in Open Science OVGU and made available to the scientific community via Open Access.
The information accumulated in the SPECTR-W3 ADB contains over 450,000 records and includes factual experimental and theoretical data on ionization potentials, energy levels, wavelengths, radiation transition probabilities, oscillator strengths, and (optionally) the parameters of analytical approximations of electron-collisional cross-sections and rates for atoms and ions. Those data were extracted from publications in physical journals, proceedings of the related conferences, special-purpose publications on atomic data, and provided directly by authors. The information is supplied with references to the original sources and comments, elucidating the details of experimental measurements or calculations, where necessary and available. To date, the SPECTR-W3 ADB is the largest factual database in the world containing the information on spectral properties of multicharged ions.
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The main objective of our work is to understand the pathomechanisms of late onset neurodegenerative disorders such as Huntington's, Parkinson's, Alzheimer's and Machado Joseph disease and to develop causal therapies for them. The disease causing proteins of these illnesses have been identified, but their functions in the unaffected organism are mostly unknown. Here, we have developed a strategy combining library and matrix yeast two-hybrid screens to generate a highly connected PPI network for Huntington's disease (HD).
The Bremen Core Repository - BCR, for International Ocean Discovery Program (IODP), Integrated Ocean Discovery Program (IODP), Ocean Drilling Program (ODP), and Deep Sea Drilling Project (DSDP) cores from the Atlantic Ocean, Mediterranean and Black Seas and Arctic Ocean is operated at University of Bremen within the framework of the German participation in IODP. It is one of three IODP repositories (beside Gulf Coast Repository (GCR) in College Station, TX, and Kochi Core Center (KCC), Japan). One of the scientific goals of IODP is to research the deep biosphere and the subseafloor ocean. IODP has deep-frozen microbiological samples from the subseafloor available for interested researchers and will continue to collect and preserve geomicrobiology samples for future research.
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The Data Portal German Marine Research is a product of the Marine Network for Integrated Data Access (MaNIDA) funded cooperatively by the Helmholtz Association and the affiliated universities. The consortium aims to implement a sustainable e-infrastructure for coherent discovery, view, download and dissemination of marine research data.
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In addition to the common documentation methods of cylinder seals by rolled impression and photography, this collection also offers 3D-models and digital impressions. The 3D-scans can be performed without impacting the objects, thus reducing the risks. This method allows even the most fragile of seals to be documented, including those too delicate to be used for a rolled impression. These scans offer a true-to-scale reproduction of the seals.
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The "Flora of Bavaria" initiative with its data portal (14 million occurrence data) and Wiki representation is primarily a citizen science project. Efforts to describe and monitor the flora of Bavaria have been ongoing for 100 years. The goal of these efforts is to record all vascular plants, including newcomers, and to document threatened or former local occurrences. Being geographically largest state of Germany with a broad range of habitats, Bavaria has a special responsibility for documenting and maintaining its plant diversity . About 85% of all German vascular plant species occur in Bavaria, and in addition it has about 50 endemic taxa, only known from Bavaria (most of them occur in the Alps). The Wiki is collaboration of volunteers and local and regional Bavarian botanical societies. Everybody is welcome to contribute, especially with photos or reports of local changes in the flora. The Flora of Bavaria project is providing access to a research data repository for occurrence data powered by the Diversity Workbench database framework.
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The portal "Wissenschaftliche Sammlungen" is a project of the Coordination Office for Academic University Collections in Germany in cooperation with the Academic University and University Collections. Together we create a platform that makes information on scientific collections, activities and actors as well as metadata and digitised objects visible, searchable and scientifically usable via a web portal. The data will be freely and openly accessible via technical interfaces in standard formats and fed into national reference systems such as the German Digital Library.
RADAM portal is an interface to the network of RADAM (RADiation DAMage) Databases collecting data on interactions of ions, electrons, positrons and photons with biomolecular systems, on radiobiological effects and relevant phenomena occurring at different time, spatial and energy scales in irradiated targets during and after the irradiation. This networking system has been created by the Consortium of COST Action MP1002 (Nano-IBCT: Nano-scale insights into Ion Beam Cancer Therapy) during 2011-2014 using the Virtual Atomic and Molecular Data Center (VAMDC) standards.
Database of mass spectra of known, unknown and provisionally identified substances. MassBank is the first public repository of mass spectral data for sharing them among scientific research community. MassBank data are useful for the chemical identification and structure elucidation of chemical compounds detected by mass spectrometry.
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The CliSAP-Integrated Climate Data Center (ICDC) allows easy access to climate relevant data from in-situ measurements and satellite remote sensing. These data are important to determine the status and the changes in the climate system. Additionally some relevant re-analysis data are included, which are modeled on the basis of observational data.
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This portal applicaton brings together the data collected and published via OGC Web-services from the individual observatories and provides access of the data to the public. Therefore, it serves as a database node to provide scientists and decision makers with reliable and well accessible data and data products.
The Virtual Liver Network (VLN) represents a major research investment by the German Government focusing on work at the “bleeding edge” of Systems Biology and Systems Medicine. This Flagship Programme is tackling one of the major challenges in the life sciences: that is, how to integrate the wealth of data we have acquired post-genome, not just in a mathematical model, but more importantly in a series of models that are linked across scales to represent organ function. As the project is prototyping how to achieve true multi-scale modelling within a single organ and linking this to human physiology, it will be developing tools and protocols that can be applied to other systems, helping to drive forward the application of modelling and simulation to modern medical practice. It is the only programme of its type to our knowledge that bridges investigations from the sub-cellular through to ethically cleared patient and volunteer studies in an integrated workflow. As such, this programme is contributing significantly to the development of a new paradigm in biology and medicine.
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KiGGS is a long-term study conducted by the Robert Koch Institute (RKI) on the health of children and adolescents in Germany. The study repeatedly supplies data, representative of the country as a whole, on the health of under 18-year-olds. In addition, the children and adolescents of the first KiGGS study are repeatedly invited, and they continue to be monitored right into their adulthood.
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The Network for the Detection of Atmospheric Composition Change (NDACC), a major contributor to the worldwide atmospheric research effort, consists of a set of globally distributed research stations providing consistent, standardized, long-term measurements of atmospheric trace gases, particles, spectral UV radiation reaching the Earth's surface, and physical parameters, centered around the following priorities.