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Found 166 result(s)
Project Achilles is a systematic effort aimed at identifying and cataloging genetic vulnerabilities across hundreds of genomically characterized cancer cell lines. The project uses genome-wide genetic perturbation reagents (shRNAs or Cas9/sgRNAs) to silence or knock-out individual genes and identify those genes that affect cell survival. Large-scale functional screening of cancer cell lines provides a complementary approach to those studies that aim to characterize the molecular alterations (e.g. mutations, copy number alterations) of primary tumors, such as The Cancer Genome Atlas (TCGA). The overall goal of the project is to identify cancer genetic dependencies and link them to molecular characteristics in order to prioritize targets for therapeutic development and identify the patient population that might benefit from such targets. Project Achilles data is hosted on the Cancer Dependency Map Portal (DepMap) where it has been harmonized with our genomics and cellular models data. You can access the latest and all past datasets here: https://depmap.org/portal/download/all/
PAGER (Prompt Assessment of Global Earthquakes for Response) is an automated system that produces content concerning the impact of significant earthquakes around the world, informing emergency responders, government and aid agencies, and the media of the scope of the potential disaster. PAGER rapidly assesses earthquake impacts by comparing the population exposed to each level of shaking intensity with models of economic and fatality losses based on past earthquakes in each country or region of the world. Earthquake alerts – which were formerly sent based only on event magnitude and location, or population exposure to shaking – now will also be generated based on the estimated range of fatalities and economic losses. PAGER uses these earthquake parameters to calculate estimates of ground shaking by using the methodology and software developed for ShakeMaps. ShakeMap sites provide near-real-time maps of ground motion and shaking intensity following significant earthquakes. These maps are used by federal, state, and local organizations, both public and private, for post-earthquake response and recovery, public and scientific information, as well as for preparedness exercises and disaster planning.
Originally named the Radiation Belt Storm Probes (RBSP), the mission was re-named the Van Allen Probes, following successful launch and commissioning. For simplicity and continuity, the RBSP short-form has been retained for existing documentation, file naming, and data product identification purposes. The RBSPICE investigation including the RBSPICE Instrument SOC maintains compliance with requirements levied in all applicable mission control documents.
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Various information, such as xylarium data with wood specimens collected since 1944, atmospheric observation data using the MU radar and other instruments, space-plasma data observed with GEOTAIL satellite, are now combined as Database of Humanosphere and served for public use. Proposals for scientific and technological use are always welcome.
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Database of ancient sources concerning Roman Water Law. Specific legal sources, e.g. from the Corpus Iuris Civilis or the Codex Theodosianus, and literary sources, for example from Cicero, Frontinus, Hyginus, Siculus Flaccus or Vitruvius, were collected to give an overview of water related legal problems in ancient Rome. Furthermore, the aim of the database is to classify these sources into different legal topics, in order to facilitate the research for sources concerning specific questions regarding Roman Water Law.
The Rotterdam Ophthalmic Data Repository (ROD-Rep) contains data sets related to ophthalmology that the Rotterdam Ophthalmic Institute has made freely available for researchers worldwide. This portal is an initiative of the Rotterdam Ophthalmic Institute, which is the research institute of the Rotterdam Eye Hospital. It provides the datasets from ophthalmic research (includes measurements such as visual fields and various imaging modalities, grades, etc.) for sharing and re-use to accelerate multi-disciplinary research, resulting in better ophthalmic care. The portal is the successor of the ORGIDS (or Open Rotterdam Glaucoma Imaging Data Sets site); which was an initiative of Koen Vermeer, Hans Lemij and Netty Dorrestijn and initial financial support was provided by Stichting Glaucoomfonds (The Netherlands).
RUresearch Data Portal is a subset of RUcore (Rutgers University Community Repository), provides a platform for Rutgers researchers to share their research data and supplementary resources with the global scholarly community. This data portal leverages all the capabilities of RUcore with additional tools and services specific to research data. It provides data in different clusters (research-genre) with excellent search facility; such as experimental data, multivariate data, discrete data, continuous data, time series data, etc. However it facilitates individual research portals that include the Video Mosaic Collaborative (VMC), an NSF-funded collection of mathematics education videos for Teaching and Research. Its' mission is to maintain the significant intellectual property of Rutgers University; thereby intended to provide open access and the greatest possible impact for digital data collections in a responsible manner to promote research and learning.
Since 1898 the Swiss Lawyers Society edits a collection of law sources which had been created on Swiss territory up to 1798, the Collection of Swiss Law Sources. The Collection contains material from the early middle ages until early modern times (1798). Over 100 volumes, or more than 70,000 pages of source material and comments from all language regions of Switzerland have been published so far.
The Satellite Application Facility on Climate Monitoring (CM SAF) develops, produces, archives and disseminates satellite-data-based products in support to climate monitoring. The product suite mainly covers parameters related to the energy & water cycle and addresses many of the Essential Climate Variables as defined by GCOS (GCOS 138). The CM SAF produces both Enviromental Data Records and Climate Data Records.
SeaBASS, the publicly shared archive of in situ oceanographic and atmospheric data maintained by the NASA Ocean Biology Processing Group (OBPG). High quality in situ measurements are prerequisite for satellite data product validation, algorithm development, and many climate-related inquiries. As such, the NASA Ocean Biology Processing Group (OBPG) maintains a local repository of in situ oceanographic and atmospheric data to support their regular scientific analyses. The SeaWiFS Project originally developed this system, SeaBASS, to catalog radiometric and phytoplankton pigment data used their calibration and validation activities. To facilitate the assembly of a global data set, SeaBASS was expanded with oceanographic and atmospheric data collected by participants in the SIMBIOS Program, under NASA Research Announcements NRA-96 and NRA-99, which has aided considerably in minimizing spatial bias and maximizing data acquisition rates. Archived data include measurements of apparent and inherent optical properties, phytoplankton pigment concentrations, and other related oceanographic and atmospheric data, such as water temperature, salinity, stimulated fluorescence, and aerosol optical thickness. Data are collected using a number of different instrument packages, such as profilers, buoys, and hand-held instruments, and manufacturers on a variety of platforms, including ships and moorings.
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SAGE is a data and research platform that enables the secondary use of data related to child and youth development, health and well-being. It currently contains research data, and at a later stage we aim to also house administrative and community service delivery data. Technical infrastructure and governance processes are in place to ensure ethical use and the privacy of participants. This dataverse provides metadata for the various data holdings available in SAGE (Secondary Analysis to Generate Evidence), a research data repository based in Edmonton Alberta and an intiative of PolicyWise for Children & Families. In general, SAGE contains data holdings too sensitive for open access. Each study lists a security level which indicates the procedure required to access the data.
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The Service Centre of the Federal Government for Geo-Information and Geodesy (Dienstleistungszentrum des Bundes für Geoinformation und Geodäsie - DLZ) provides geodetic and geo-topographic reference data of the Federal Government centrally to federal institutions, public administrations, economy, science and citizens. The establishment of the Service Centre is based on the Federal Geographic Reference Data Act (Bundesgeoreferenzdatengesetz − BGeoRG), which came into effect on 1 November 2012. This act regulates use, quality and technology of the geodetic and geo-topographic reference systems, networks and data.
The SICAS Medical Image Repository is a freely accessible repository containing medical research data including medical images, surface models, clinical data, genomics data and statistical shape models. The data can freely be organized and shared on SMIR and made publicly accessible with a DOI. Dedicated data sets are organized as collections of anatomical regions (e.g Cochlea). The data can be filtered using a modular search and accessed on the web or through the SMIR API.
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One of the world’s largest banks of biological, psychosocial and clinical data on people suffering from mental health problems. The Signature center systematically collects biological, psychosocial and clinical indicators from patients admitted to the psychiatric emergency and at four points throughout their journey in the hospital: upon arrival to the emergency room (state of crisis), at the end of their hospital stay, as well as at the beginning and the end of outpatient treatment. For all hospital clients who agree to participate, blood specimens are collected for the purpose of measuring metabolic, genetic, toxic and infectious biomarkers, while saliva samples are collected to measure sex hormones and hair samples are collected to measure stress hormones. Questionnaire has been selected to cover important dimensional aspects of mental illness such as Behaviour and Cognition (Psychosis, Depression, Anxiety, Impulsiveness, Aggression, Suicide, Addiction, Sleep),Socio-demographic Profile (Spiritual beliefs, Social functioning, Childhood experiences, Demographic, Family background) and Medical Data (Medication, Diagnosis, Long-term health, RAMQ data). On 2016, May there are more than 1150 participants and 400 for the longitudinal Follow-Up
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SilkDB is a database of the integrated genome resource for the silkworm, Bombyx mori. This database provides access to not only genomic data including functional annotation of genes, gene products and chromosomal mapping, but also extensive biological information such as microarray expression data, ESTs and corresponding references. SilkDB will be useful for the silkworm research community as well as comparative genomics
The Site Survey Data Bank (SSDB) is a repository for site survey data submitted in support of International Ocean Discovery Program (IODP) proposals and expeditions. SSDB serves different roles for different sets of users.
SOHO, the Solar & Heliospheric Observatory, is a project of international collaboration between ESA and NASA to study the Sun from its deep core to the outer corona and the solar wind. SOHO was launched on December 2, 1995. The SOHO spacecraft was built in Europe by an industry team led by prime contractor Matra Marconi Space (now EADS Astrium) under overall management by ESA. The twelve instruments on board SOHO were provided by European and American scientists.
The Southern California Earthquake Data Center (SCEDC) operates at the Seismological Laboratory at Caltech and is the primary archive of seismological data for southern California. The 1932-to-present Caltech/USGS catalog maintained by the SCEDC is the most complete archive of seismic data for any region in the United States. Our mission is to maintain an easily accessible, well-organized, high-quality, searchable archive for research in seismology and earthquake engineering.
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KiGGS is a long-term study conducted by the Robert Koch Institute (RKI) on the health of children and adolescents in Germany. The study repeatedly supplies data, representative of the country as a whole, on the health of under 18-year-olds. In addition, the children and adolescents of the first KiGGS study are repeatedly invited, and they continue to be monitored right into their adulthood.
To understand the global surface energy budget is to understand climate. Because it is impractical to cover the earth with monitoring stations, the answer to global coverage lies in reliable satellite-based estimates. Efforts are underway at NASA and universities to develop algorithms to do this, but such projects are in their infancy. In concert with these ambitious efforts, accurate and precise ground-based measurements in differing climatic regions are essential to refine and verify the satellite-based estimates, as well as to support specialized research. To fill this niche, the Surface Radiation Budget Network (SURFRAD) was established in 1993 through the support of NOAA's Office of Global Programs.
The Swiss HIV Cohort Study (SHCS), established in 1988, is a systematic longitudinal study enrolling HIV-infected individuals in Switzerland. It is a collaboration of all Swiss University Hospital infectious disease outpatient clinics, two large cantonal hospitals, all with affiliated laboratories, and with affiliated smaller hospitals and private physicians carrying for HIV patients. The Swiss Mother and Child HIV Cohort Study (MoCHiV) is integrated into the SHCS. It aims at preventing mother to child transmission and enrolls HIV-infected pregnant women and their children. The SHCS involves practically all researchers being active in patient-oriented HIV research in Switzerland. The clinics can delegate recruitment of participants and follow-up visits to other outpatient clinics or to specialized private physicians, provided that the requirements of the protocol can be entirely fulfilled and controlled. The laboratories can contract other laboratories for some of the analyses.
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This portal applicaton brings together the data collected and published via OGC Web-services from the individual observatories and provides access of the data to the public. Therefore, it serves as a database node to provide scientists and decision makers with reliable and well accessible data and data products.
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The TerMEx program addresses, within the framework of circum-Mediterranean cooperation, two sets of major challenges: (1) the scientific challenges of the Mediterranean deep Earth dynamics, its basin deposits and its interactions with climate, and (2) the societal challenges associated with natural hazards, resources and climate change. The database aims at documenting, storing and distributing the data produced or used by the TerMEx community. This community is not exclusive and we encourage researchers of associated and related programs in the Mediterranean (e.g. Actions Marges and ESF-TopoMed) to join-in the community.
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Tethys is an Open Access Research Data Repository of the GeoSphere Austria, which publishes and distributes georeferenced geoscientific research data generated at and in cooperation with the GeoSphere Austria. The research data publications and the associated metadata are predominantly provided in German or in English. The abstracts are provided in both languages. Tethys aims to provide published data sets as open data and in accordance with the FAIR Data Principles, findable, accessible, interoperable and reusable.
TAED is a database of phylogenetically indexed gene families. It contains multiple sequence alignments from MAFFT1, maximum likelihood phylogenetic trees from PhyML2, bootstrap values for each node, dN/dS ratios for each lineage from the free ratios model in PAML3, and labels for each node of speciation or duplication from gene tree/species tree reconciliation using SoftParsMap4. The phylogenetic indexing enables simultaneous viewing of lineages with high dN/dS that occurred along the same species tree branches. Resources from the Protein Data Bank (PDB) and the Kyoto Encyclopedia of Genes and Genomes (KEGG)5, have been incorporated into the TAED analysis to detect substitutions along each branch within the phylogenetic tree and to assess selection within pathways.