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Found 15 result(s)
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<<<!!!<<< This repository is no longer available. >>>!!!>>> A human interactome map. The sequencing of the human genome has provided a surprisingly small number of genes, indicating that the complex organization of life is not reflected in the gene number but, rather, in the gene products – that is, in the proteins. These macromolecules regulate the vast majority of cellular processes by their ability to communicate with each other and to assemble into larger functional units. Therefore, the systematic analysis of protein-protein interactions is fundamental for the understanding of protein function, cellular processes and, ultimately, the complexity of life. Moreover, interactome maps are particularly needed to link new proteins to disease pathways and the identification of novel drug targets.
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<<<!!!<<< This repository is no longer available. >>>!!!>>> The main objective of our work is to understand the pathomechanisms of late onset neurodegenerative disorders such as Huntington's, Parkinson's, Alzheimer's and Machado Joseph disease and to develop causal therapies for them. The disease causing proteins of these illnesses have been identified, but their functions in the unaffected organism are mostly unknown. Here, we have developed a strategy combining library and matrix yeast two-hybrid screens to generate a highly connected PPI network for Huntington's disease (HD).
The Human Mortality Database (HMD) was created to provide detailed mortality and population data to researchers, students, journalists, policy analysts, and others interested in the history of human longevity. The Human Mortality Database (HMD) contains original calculations of death rates and life tables for national populations (countries or areas), as well as the input data used in constructing those tables. The input data consist of death counts from vital statistics, plus census counts, birth counts, and population estimates from various sources.
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The repository is no longer available <<<!!!<<< The Senate Commission on Oceanography planned and coordinated the activities of the DFG in the field of marine research from 1959 until 2017. Most notably, it advised on matters pertaining to the research vessels METEOR and (from 2006 onwards) MARIA S. MERIAN, which are co-funded by the DFG. The focus was on the review process and evaluation of proposed voyages for these two ships. The Expert Research Vessel Panel (GPF) appointed by the BMBF and DFG, which is responsible for the review process for proposed voyages for all global, oceanic and regional German research vessels within the framework of a joint procedure developed by the BMBF, DFG and HGF, was constituted on 7 March 2018 and thus took on this task concerning METEOR and MARIA S. MERIAN from the Senate Commission on Oceanography. More information on the new review process can be found on the German Research Vessels Portal. https://www.portal-forschungsschiffe.de/index.php?index=53. >>>!!!>>>
The Bremen Core Repository - BCR, for International Ocean Discovery Program (IODP), Integrated Ocean Discovery Program (IODP), Ocean Drilling Program (ODP), and Deep Sea Drilling Project (DSDP) cores from the Atlantic Ocean, Mediterranean and Black Seas and Arctic Ocean is operated at University of Bremen within the framework of the German participation in IODP. It is one of three IODP repositories (beside Gulf Coast Repository (GCR) in College Station, TX, and Kochi Core Center (KCC), Japan). One of the scientific goals of IODP is to research the deep biosphere and the subseafloor ocean. IODP has deep-frozen microbiological samples from the subseafloor available for interested researchers and will continue to collect and preserve geomicrobiology samples for future research.
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The SHIP study´s main aims include the investigation of health in all its aspects and complexity involving the collection and assessment of data relevant to the prevalence and incidence of common, population-relevant diseases and their risk factors.
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With its “Blood Donor BIOBANK”, the Bavarian Red Cross (BRK) Blood Donor Service offers a unique and innovative resource for biomarker research: the world’s first blood donor based biobank. Biobanks as collections of biological material together with associated medical data open new possibilities for the development of new targeted diagnostics and therapies. The BRK Blood Donor Service maintains a unique collection of over 3 million blood samples, making it one of the largest sample collections worldwide. Every working day 2,000 new samples are added to the collection.
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LIAS is a global information system for Lichenized and Non-Lichenized Ascomycetes. It includes several interoperable data repositories. In recent years, the two core components ‘LIAS names’ and ‘LIAS light’ have been much enlarged. LIAS light is storing phenotypic trait data. They includes > 10,700 descriptions (about 2/3 of all known lichen species), each with up to 75 descriptors comprising 2,000 traits (descriptor states and values), including 800 secondary metabolites. 500 traits may have biological functions and more than 1,000 may have phylogenetic relevance. LIAS is thus one of the most comprehensive trait databases in organismal biology. The online interactive identification key for more than 10,700 lichens is powered by the Java applet NaviKey and has been translated into 19 languages (besides English) in cooperation with lichenologists worldwide. The component ‘LIAS names’ is a platform for managing taxonomic names and classifications with currently >50,000 names, including the c. 12,000 accepted species and recognized synonyms. The LIAS portal contents, interfaces, and databases run on servers of the IT Center of the Bavarian Natural History Collections and are maintained there. 'LIAS names' and ‘LIAS light’ also deliver content data to the Catalogue of Life, acting as the Global Species Database (GSD) for lichens. LIAS gtm is a database for visualising the geographic distribution of lichen traits. LIAS is powered by the Diversity Workbench database framework with several interfaces for data management and publication. The LIAS long-term project was initiated in the early 1990s and has since been continued with funding from the DFG, the BMBF, and the EU.
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The EuMMCR (European Mouse Mutant cell Repository) is the mouse ES cell distribution unit in Europe. The EuMMCR unit distributes targeting vectors and mutant ES cell lines produced in the EUCOMM and EUCOMMTOOLS consortia.
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The WSI-Datenzentrum is a service provided by the Institute for Social and Economic Research (WSI). It collects and presents primary and secondary data on e.g. working conditions, co-determination or social policy. Primary data collected are primarily the WSI works councils surveys. Interested academics can use the works councils surveys collected from 2005 to 2011. The records are available to everyone and free of charge after contacting the repository owner and signing a data usage statement.
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<<<<<!!! With the implementation of GlyTouCan (https://glytoucan.org/) the mission of GlycomeDB comes to an end. !!!>>>>> With the new database, GlycomeDB, it is possible to get an overview of all carbohydrate structures in the different databases and to crosslink common structures in the different databases. Scientists are now able to search for a particular structure in the meta database and get information about the occurrence of this structure in the five carbohydrate structure databases.
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In the Wolfenbüttel Digital Library the Herzog August Bibliothek presents in digital facsimile selected items from its collections which are rare, outstanding, frequently used, or currently most relevant for research. All digitized titles may be accessed not only here, but also via the PICA-OPAC as long as they are monographs. The OPAC allows you to search for digitized books separately by limiting the search options within the database using the term Online Resources. Projects which provide additional indexing comprise a project-specific database, an inventory of digitized titles, information about tools and techniques, and references to literature. Here the main objective is to provide search facilities outside the scope of usual bibliographic description, such as page-related indexing.