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Found 157 result(s)
STRING is a database of known and predicted protein interactions. The interactions include direct (physical) and indirect (functional) associations; they are derived from four sources: - Genomic Context - High-throughput Experiments - (Conserved) Coexpression - Previous Knowledge STRING quantitatively integrates interaction data from these sources for a large number of organisms, and transfers information between these organisms where applicable.
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BRENDA is the main collection of enzyme functional data available to the scientific community worldwide. The enzymes are classified according to the Enzyme Commission list of enzymes. It is available free of charge for via the internet (http://www.brenda-enzymes.org/) and as an in-house database for commercial users (requests to our distributor Biobase). The enzymes are classified according to the Enzyme Commission list of enzymes. Some 5000 "different" enzymes are covered. Frequently enzymes with very different properties are included under the same EC number. BRENDA includes biochemical and molecular information on classification, nomenclature, reaction, specificity, functional parameters, occurrence, enzyme structure, application, engineering, stability, disease, isolation, and preparation. The database also provides additional information on ligands, which function as natural or in vitro substrates/products, inhibitors, activating compounds, cofactors, bound metals, and other attributes.
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With ARS - Antimicrobial Resistance Surveillance in Germany - the infrastructure for a nationwide surveillance of antimicrobial resistance has been established, which covers both the inpatient medical care and the ambulatory care sector. This is intended to reliable data on the epidemiology of antimicrobial resistance in Germany and differential statements provided by structural features of the health care and by region are possible. ARS is designed as a laboratory-based surveillance system for continuous collection of resistance data from routine for the full range of clinically relevant bacterial pathogens. Project participants and thus data suppliers are laboratories that analyze samples of medical facilities and doctors' offices microbiologically.
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The FDZ-DZA (Forschungsdatenzentrum DZA) is a facility of the German Centre of Gerontology (Deutsches Zentrum für Altersfragen, DZA) and has received accreditation as research data center DZA by the German Data Forum (RatSWD). Its main task is to make data of the German Ageing Survey DEAS and the German Survey on Volunteering (FWS) accessible to researchers by providing user-friendly Scientific Use Files (SUF), documentation of the contents and instruments as well support for scholars using the data.
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The Research Data Centre of the Robert Koch Institute (FDZ RKI) publishes the data of population-representative health surveys in the form of public use files (PUFs).The main purpose of health surveys is to generate a maximum amount of information on the state of health and health-related behaviour of Germany's resident population while ensuring an optimum use of funds. The methodology - i.e. the sample design, the principles on operationalization and measurement, and data-collection techniques - is largely modelled on the tried-and-tested methods of empirical social research. Health interview surveys (HIS) use established survey techniques such as filling out questionnaires, computer-assisted telephone interviews (CATI), computer-assisted personal interviews (CAPI), and online polling via the internet or email. The main difference compared to purely sociological surveys lies in the additional biomedical examinations, tests and medical-biochemical measurements, which generate significant added value in addition to the results of the surveys; this part is referred to internationally as the health examination survey (HES).
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Human biomaterial banks (short: biobanks) are collections of human body substances (i.e. blood, DNA, urine or tissue) connected with disease specific information. This allow for research of relations between deseases and underlying (molecular) modifications and paves the way for developing target-oriented therapies ("personalized medicine"). The biobank material arises from samples taken for therapeutical or diagnostic reasons or is extracted in the context of clinical trials. An approval for usage by the patient is always needed prior to any research activities.
The PLANKTON*NET data provider at the Alfred Wegener Institute for Polar and Marine Research is an open access repository for plankton-related information. It covers all types of phytoplankton and zooplankton from marine and freshwater areas. PLANKTON*NET's greatest strength is its comprehensiveness as for the different taxa image information as well as taxonomic descriptions can be archived. PLANKTON*NET also contains a glossary with accompanying images to illustrate the term definitions. PLANKTON*NET therefore presents a vital tool for the preservation of historic data sets as well as the archival of current research results. Because interoperability with international biodiversity data providers (e.g. GBIF) is one of our aims, the architecture behind the new planktonnet@awi repository is observation centric and allows for mulitple assignment of assets (images, references, animations, etc) to any given observation. In addition, images can be grouped in sets and/or assigned tags to satisfy user-specific needs . Sets (and respective images) of relevance to the scientific community and/or general public have been assigned a persistant digital object identifier (DOI) for the purpose of long-term preservation (e.g. set ""Plankton*Net celebrates 50 years of Roman Treaties"", handle: 10013/de.awi.planktonnet.set.495)"
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A human interactome map. The sequencing of the human genome has provided a surprisingly small number of genes, indicating that the complex organization of life is not reflected in the gene number but, rather, in the gene products – that is, in the proteins. These macromolecules regulate the vast majority of cellular processes by their ability to communicate with each other and to assemble into larger functional units. Therefore, the systematic analysis of protein-protein interactions is fundamental for the understanding of protein function, cellular processes and, ultimately, the complexity of life. Moreover, interactome maps are particularly needed to link new proteins to disease pathways and the identification of novel drug targets.
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GeoReM is a Max Planck Institute database for reference materials of geological and environmental interest, such as rock powders, synthetic and natural glasses as well as mineral, isotopic, biological, river water and seawater reference materials. GeoReM contains published analytical data and compilation values (major and trace element concentrations and mass fractions, radiogenic and stable isotope ratios). GeoReM contains all important metadata about the analytical values such as uncertainty, analytical method and laboratory. Sample information and references are also included. GeoReM complements the three earthchem databases: GEOROC, NAVDAT and PETDB.
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The project brings together national key players providing environmentally related biological data and services to develop the ‘German Federation for Biological Data' (GFBio). The overall goal is to provide a sustainable, service oriented, national data infrastructure facilitating data sharing and stimulating data intensive science in the fields of biological and environmental research.
DBpedia is a crowd-sourced community effort to extract structured information from Wikipedia and make this information available on the Web. DBpedia allows you to ask sophisticated queries against Wikipedia, and to link the different data sets on the Web to Wikipedia data. We hope that this work will make it easier for the huge amount of information in Wikipedia to be used in some new interesting ways. Furthermore, it might inspire new mechanisms for navigating, linking, and improving the encyclopedia itself.
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In the digital collections, you can take a look at the digitized prints from the holdings of the ULB Düsseldorf free of cost. In special collections, the ULB unites rare, valuable and unique parts of holdings that are installed as an ensemble. Deposita, unpublished works, donations, acquisition of rare books etc. were and are an important source for the constant growth of the library. These treasures and specialties - beyond their academic value - also contribute substantially to the profile of the ULB.
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The German Neuroinformatics Node's data infrastructure (GIN) services provide a platform for comprehensive and reproducible management and sharing of neuroscience data. Building on well established versioning technology, GIN offers the power of a web based repository management service combined with a distributed file storage. The service addresses the range of research data workflows starting from data analysis on the local workstation to remote collaboration and data publication.
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The RAMEDIS system is a platform independent, web-based information system for rare metabolic diseases based on filed case reports. It was developed in close cooperation with clinical partners to allow them to collect information on rare metabolic diseases with extensive details, e.g. about occurring symptoms, laboratory findings, therapy and molecular data.
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The JenAge Ageing Factor Database AgeFactDB is aimed at the collection and integration of ageing phenotype and lifespan data. Ageing factors are genes, chemical compounds or other factors such as dietary restriction, for example. In a first step ageing-related data are primarily taken from existing databases. In addition, new ageing-related information is included both by manual and automatic information extraction from the scientific literature. Based on a homology analysis, AgeFactDB also includes genes that are homologous to known ageing-related genes. These homologs are considered as candidate or putative ageing-related genes.
As with most biomedical databases, the first step is to identify relevant data from the research community. The Monarch Initiative is focused primarily on phenotype-related resources. We bring in data associated with those phenotypes so that our users can begin to make connections among other biological entities of interest. We import data from a variety of data sources. With many resources integrated into a single database, we can join across the various data sources to produce integrated views. We have started with the big players including ClinVar and OMIM, but are equally interested in boutique databases. You can learn more about the sources of data that populate our system from our data sources page https://monarchinitiative.org/about/sources.
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coastMap offers campaign data, model analysis and thematic maps predominantly in the Biogeosciences. Spotlights explain in a nutshell important topics of the research conducted for the interested public. The portal offers applications to visualise and download field and laboratory work and to connect the information with interactive maps. Filter functions allow the user to search for general topics like a marine field of interest or single criteria, for example a specific ship campaign or one of 1000 measured parameters. The Model Analysis Tool uses a "Big Data" approach and allows expert of different disciplines to access detailed and high-resolution oceanographic model data. An interface is provided to statistically examine and download subsets of model-derived data.
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On this server you'll find 69 items of primary data of the University of Munich. Scientists / students of all faculties of LMU and of institutions that cooperate with the LMU are invited to deposit their research data on this platform.
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The edoc-Server, start 1998, is the Institutional Repository of the Humboldt-Universität zu Berlin and offers the posibility of text- and data-publications. Every item is published for Open-Access with an optional embargo period of up to five years. Data publications since 01.01.2018.
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BExIS is the online data repository and information system of the Biodiversity Exploratories Project (BE). The BE is a German network of biodiversity related working groups from areas such as vegetation and soil science, zoology and forestry. Up to three years after data acquisition, the data use is restricted to members of the BE. Thereafter, the data is usually public available (https://www.bexis.uni-jena.de/PublicData/PublicDataDefault.aspx).
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OpARA (Open Access Repository and Archive) is the repository for digital research data of the TU Dresden (TUD) and the TU Bergakademie Freiberg (TUBAF). It offers researchers the possibility of archiving their digital research data and optionally making it accessible to third parties under an Open Access license.