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Found 9 result(s)
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Covalent DNA modifications have been found in numerous organisms and more are continually being discovered and characterized, as detection methods improve. Many of these modifications can affect the conformation of the DNA double helix, often resulting in downstream effects upon transcription factor binding. Some of these modifications have been demonstrated to be stable, while others are viewed as merely transient. DNAmod catalogues information on known DNA modifications, of which the well-known 5-methylcytosine is only one. It aims to profile modifications' properties, building upon data contained within the Chemical Entities of Biological Interest (ChEBI) database. It also provides literature citations and includes curated annotations on mapping techniques and natural occurrence information.
Pandora is an open data platform devoted to the study of the human story. Data may be deposited from various disciplines and research topics that investigate humans from their early beginnings until present in addition to their environmental context (e.g. archeology, anthropology history, ancient DNA, isotopes, zooarchaeology, archaeobotany, and paleoenvironmental and paleoclimatic studies, etc.). Pandora allows autonomous data communities to self-manage their webspace and community membership. Data communities self-curate their data plus other supporting resources. Datasets may be assigned a new DOI and a schema markup is employed to improve data findability. Pandora also allows for links to datasets stored externally and having previously assigned DOIs. Through this, it becomes possible to establish data networks devoted to specific topics that may combine a mix of datasets stored either within Pandora or externally.
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The purpose of the Biobank is to accelerate future research projects and build health monitoring opportunities on a nationally-representative sample of Canadians. The Biobank receives samples from surveys like CHMS or CCAHS that collect dried blood spot, blood, urine, and saliva samples from consenting participants. These samples are stored in a secure location for future health studies. To obtain approval for the use of these samples, research projects undergo a thorough scientific, ethical, and security review process.
The Progenetix database provides an overview of copy number abnormalities in human cancer from currently 32548 array and chromosomal Comparative Genomic Hybridization (CGH) experiments, as well as Whole Genome or Whole Exome Sequencing (WGS, WES) studies. The cancer profile data in Progenetix was curated from 1031 articles and represents 366 different cancer types, according to the International classification of Diseases in Oncology (ICD-O).
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Bioresources, often referred to as biological resources, are essential experimental research materials for life science and bioindustry. Under the three principles of “Trust”, “Sustainability” and “Leadership”, RIKEN BRC is committed to receiving deposition/donation of bioresources from the research community, confirming the authenticity of bioresources by rigorous quality examination, preserving, and distributing them back to the research community. f you wish to search quickly or to search multiple bioresources (mouse, cell, plant, microorganism, gene) simultaneously, we recommend to search from the Top Page. At the Top page, bioresource search and Google-based site search are available.
BBMRI-ERIC is a European research infrastructure for biobanking. We bring together all the main players from the biobanking field – researchers, biobankers, industry, and patients – to boost biomedical research. To that end, we offer quality management services, support with ethical, legal and societal issues, and a number of online tools and software solutions. Ultimately, our goal is to make new treatments possible. The Directory is a tool to share aggregate information about the biobanks that are willing external collaboration. It is based on the MIABIS 2.0 standard, which describes the samples and data in the biobanks at an aggregated level.
GeneWeaver combines cross-species data and gene entity integration, scalable hierarchical analysis of user data with a community-built and curated data archive of gene sets and gene networks, and tools for data driven comparison of user-defined biological, behavioral and disease concepts. Gene Weaver allows users to integrate gene sets across species, tissue and experimental platform. It differs from conventional gene set over-representation analysis tools in that it allows users to evaluate intersections among all combinations of a collection of gene sets, including, but not limited to annotations to controlled vocabularies. There are numerous applications of this approach. Sets can be stored, shared and compared privately, among user defined groups of investigators, and across all users.