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Found 24 result(s)
OrthoMCL is a genome-scale algorithm for grouping orthologous protein sequences. It provides not only groups shared by two or more species/genomes, but also groups representing species-specific gene expansion families. So it serves as an important utility for automated eukaryotic genome annotation. OrthoMCL starts with reciprocal best hits within each genome as potential in-paralog/recent paralog pairs and reciprocal best hits across any two genomes as potential ortholog pairs. Related proteins are interlinked in a similarity graph. Then MCL (Markov Clustering algorithm,Van Dongen 2000; www.micans.org/mcl) is invoked to split mega-clusters. This process is analogous to the manual review in COG construction. MCL clustering is based on weights between each pair of proteins, so to correct for differences in evolutionary distance the weights are normalized before running MCL.
ModelDB is a curated database of published models in the broad domain of computational neuroscience. It addresses the need for access to such models in order to evaluate their validity and extend their use. It can handle computational models expressed in any textual form, including procedural or declarative languages (e.g. C++, XML dialects) and source code written for any simulation environment. The model source code doesn't even have to reside inside ModelDB; it just has to be available from some publicly accessible online repository or WWW site.
TriTrypDB is an integrated genomic and functional genomic database for pathogens of the family Trypanosomatidae, including organisms in both Leishmania and Trypanosoma genera. TriTrypDB and its continued development are possible through the collaborative efforts between EuPathDB, GeneDB and colleagues at the Seattle Biomedical Research Institute (SBRI).
Country
With more than 60 years of experience, Toronto and Region Conservation Authority (TRCA) is one of 36 Conservation Authorities in Ontario, created to safeguard and enhance the health and well-being of watershed communities through the protection and restoration of the natural environment and the ecological services the environment provides. At TRCA, we are working towards providing free and open access to our data and information, in both accessible and machine readable formats, to ensure it’s available and easy to consume. Improving access to TRCA’s data and information will provide transparency into the decision making process and will improve accountability while increasing the public’s understanding and engagement with the organization.
Country
An open data sharing platform resulting from collaboration between cities and the Government of Quebec.
Country
By opening its data to everyone, Ville de Montréal allows it to be reused for various purposes, including commercial ones. The results of this reuse can then be shared in the community, creating a multiplier effect. The data released and reused thus generate benefits in the economic, cultural, social and technological spheres.
CryptoDB is an integrated genomic and functional genomic database for the parasite Cryptosporidium and other related genera. CryptoDB integrates whole genome sequence and annotation along with experimental data and environmental isolate sequences provided by community researchers. The database includes supplemental bioinformatics analyses and a web interface for data-mining.
Country
AURIN is a collaborative national network of leading researchers and data providers across the academic, government, and private sectors. We provide a one-stop online workbench with access to thousands of multidisciplinary datasets, from over 100 different data sources.
AmoebaDB belongs to the EuPathDB family of databases and is an integrated genomic and functional genomic database for Entamoeba and Acanthamoeba parasites. In its first iteration (released in early 2010), AmoebaDB contains the genomes of three Entamoeba species (see below). AmoebaDB integrates whole genome sequence and annotation and will rapidly expand to include experimental data and environmental isolate sequences provided by community researchers . The database includes supplemental bioinformatics analyses and a web interface for data-mining.
ToxoDB is a genome database for the genus Toxoplasma, a set of single-celled eukaryotic pathogens that cause human and animal diseases, including toxoplasmosis.
Country
The Canada Open Data Project provides Government of Canada data to the public as potential driver for economic innovation. Searchable and browsable raw data is available for download, and the public can recommend specific data be made available.
MetabolomeXchange.org delivers the mechanisms needed for disseminating the data to the metabolomics community at large (both metabolomics researchers and databases). The main objective is to make it easier for metabolomics researchers to become aware of newly released, publicly available, metabolomics datasets that may be useful for their research. MetabolomeXchange contains datasets from different data providers: MetaboLights, Metabolomic Repository Bordeaux, Metabolomics Workbench, and Metabolonote
Content type(s)
A genome database for the genus Piroplasma. PiroplasmaDB is a member of pathogen-databases that are housed under the NIAID-funded EuPathDB Bioinformatics Resource Center (BRC) umbrella.
Country
GovData the data portal for Germany offers consistent and central access to administrative data at the federal, state, and local level. Objective is to make data more available and easier to use at a single location. As set out in the concept of "open data", we attempt to facilitate the use of open licenses and to increase the supply of machine-readable raw data.
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<<<!!!<<< The repository is no longer available 2020-02-21: no more access to "Environment Climate Data Sweden" >>>!!!<<< The transfer of records from the Environment Climate Data Sweden (ECDS) database to the Swedish National Dataservice (SND) https://www.re3data.org/repository/r3d100010146 was completed in 2019. SND is a national research infrastructure with a primary function to support the accessibility, preservation, and re-use of research data and related materials. You can search the SND research data portal specifically for Natural Science or Agricultural and Veterinary Sciences datasets. Data descriptions with associated datasets, or a direct reference/URL to data, have been migrated from the ECDS portal to the SND research data portal. Previous links to these data are now automatically directed to an SND catalogue entry. Records in the ECDS catalogue that only contained metadata (ie information that data could be accessed through another portal, e.g. Pangea), now link directly to the portal in question. If you want to make one of those data descriptions searchable in SND’s catalogue, please contact SND on snd@snd.gu.se. A small number of records were neither migrated to SND nor redirected to external providers, and they redirect. Contact SND on snd@snd.gu.se if you want more information about the closing of the ECDS portal and the migration of data descriptions to SND’s research data catalogue.
Giardia lamblia is a significant, environmentally transmitted, human pathogen and an amitochondriate protist. It is a major contributor to the enormous worldwide burden of human diarrheal diseases, yet the basic biology of this parasite is not well understood. No virulence factor has been identified. The Giardia lamblia genome contains only 12 million base pairs distributed onto five chromosomes. Its analysis promises to provide insights about the origins of nuclear genome organization, the metabolic pathways used by parasitic protists, and the cellular biology of host interaction and avoidance of host immune systems. Since the divergence of Giardia lamblia lies close to the transition between eukaryotes and prokaryotes in universal ribosomal RNA phylogenies, it is a valuable, if not unique, model for gaining basic insights into genetic innovations that led to formation of eukaryotic cells. In evolutionary terms, the divergence of this organism is at least twice as ancient as the common ancestor for yeast and man. A detailed study of its genome will provide insights into an early evolutionary stage of eukaryotic chromosome organization as well as other aspects of the prokaryotic / eukaryotic divergence.