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Found 137 result(s)
Bioconductor provides tools for the analysis and comprehension of high-throughput genomic data. Bioconductor uses the R statistical programming language, and is open source and open development. It has two releases each year, and an active user community. Bioconductor is also available as an AMI (Amazon Machine Image) and a series of Docker images.
OpenWorm aims to build the first comprehensive computational model of the Caenorhabditis elegans (C. elegans), a microscopic roundworm. With only a thousand cells, it solves basic problems such as feeding, mate-finding and predator avoidance. Despite being extremely well studied in biology, this organism still eludes a deep, principled understanding of its biology. We are using a bottom-up approach, aimed at observing the worm behaviour emerge from a simulation of data derived from scientific experiments carried out over the past decade. To do so we are incorporating the data available in the scientific community into software models. We are engineering Geppetto and Sibernetic, open-source simulation platforms, to be able to run these different models in concert. We are also forging new collaborations with universities and research institutes to collect data that fill in the gaps All the code we produce in the OpenWorm project is Open Source and available on GitHub.
The Ontology Lookup Service (OLS) is a repository for biomedical ontologies that aims to provide a single point of access to the latest ontology versions. The user can browse the ontologies through the website as well as programmatically via the OLS API. The OLS provides a web service interface to query multiple ontologies from a single location with a unified output format.The OLS can integrate any ontology available in the Open Biomedical Ontology (OBO) format. The OLS is an open source project hosted on Google Code.
Cary Institute data repository allows researchers to store, share and publish their research data, supplementary information and associated metadata. Each published item is assigned a Digital Object identifier (DOI), which allows the data to be citable and sustainable. This repository is a member node of DataOne.
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A collection of high quality multiple sequence alignments for objective, comparative studies of alignment algorithms. The alignments are constructed based on 3D structure superposition and manually refined to ensure alignment of important functional residues. A number of subsets are defined covering many of the most important problems encountered when aligning real sets of proteins. It is specifically designed to serve as an evaluation resource to address all the problems encountered when aligning complete sequences. The first release provided sets of reference alignments dealing with the problems of high variability, unequal repartition and large N/C-terminal extensions and internal insertions. Version 2.0 of the database incorporates three new reference sets of alignments containing structural repeats, trans-membrane sequences and circular permutations to evaluate the accuracy of detection/prediction and alignment of these complex sequences. Within the resource, users can look at a list of all the alignments, download the whole database by ftp, get the "c" program to compare a test alignment with the BAliBASE reference (The source code for the program is freely available), or look at the results of a comparison study of several multiple alignment programs, using BAliBASE reference sets.
Bioinformatics.org serves the scientific and educational needs of bioinformatic practitioners and the general public. We develop and maintain computational resources to facilitate world-wide communications and collaborations between people of all educational and professional levels. We provide and promote open access to the materials and methods required for, and derived from, research, development and education.
A database for plant breeders and researchers to combine, visualize, and interrogate the wealth of phenotype and genotype data generated by the Triticeae Coordinated Agricultural Project (TCAP).
AgBase is a curated, open-source, Web-accessible resource for functional analysis of agricultural plant and animal gene products. Our long-term goal is to serve the needs of the agricultural research communities by facilitating post-genome biology for agriculture researchers and for those researchers primarily using agricultural species as biomedical models.
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QSAR DataBank (QsarDB) is repository for (Quantitative) Structure-Activity Relationships ((Q)SAR) data and models. It also provides open domain-specific digital data exchange standards and associated tools that enable research groups, project teams and institutions to share and represent predictive in silico models.
PSnpBind is a large database of protein–ligand complexes covering a wide range of binding pocket mutations and small molecules’ landscape. This database can be used as a source of data for different types of studies, for example, developing machine learning algorithms to predict protein–ligand affinity or mutation's effect on it which requires an extensive amount of data with a wide coverage of mutation types and small molecules. Also, studies of protein-ligand interactions and conformer orientation changes across different mutated versions of a protein can be established using data from PSnpBind.
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Australian Waterbird Surveys (AWS) is an information source of waterbird communities around Australia, based on surveys of their diversity and numbers. It relies on rigorous data collection protocols and includes more than 50 waterbird species and up to 30 years of survey data. This open source also includes the extent of flooding of thousands of wetlands observed during our surveys. As a group, waterbirds can be sentinels of the ecological health of our wetlands and rivers. We hope this free information system will help track long-term changes in the environment, provide an assessment tool for individual species, report on our national and international responsibilities and help improve the way we manage our rivers and wetlands. It has been developed with the support of research and government partners.
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Repository "Open Science Resource Atlas 2.0" aims to increase the accessibility, improve the quality and extend the reusability of science resources. Repository focuses on the digital sharing of resources of great importance to the field of science and economy. These include publications, scripts, lectures, 3D models, audio and video recordings, photos, input and output files of various computer programs, databases collecting data from various fields, machines, systems, language corpora and many others. The target group, apart from academics, students and doctoral students, is everyone interested, including entrepreneurs and, what is important and unique - disabled, blind, visually impaired and deaf people.
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'Redape' is a digital repository that aims to preserve and disseminate research data produced by the Brazilian Agricultural Research Corporation - Embrapa. It allows the organization, management and publication of data in accordance with the FAIR principles.
The British Columbia Conservation Data Centre (CDC) collects and disseminates information on plants, animals and ecosystems at risk in British Columbia. The " BC Species and Ecosystems Explorer" is a source for authoritative conservation information on approximately 7400 plants and animals, and over 600 ecological communities (ecosystems)in British Columbia. Information includes conservation status, legal designation, and ecosection values for ecological communities.
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bonndata is the institutional, FAIR-aligned and curated, cross-disciplinary research data repository for the publication of research data for all researchers at the University of Bonn. The repository is fully embedded into the University IT and Data Center and curated by the Research Data Service Center (https://www.forschungsdaten.uni-bonn.de/en). The software that bonndata is based on is the open source software Dataverse (https://dataverse.org)
CottonGen is a new cotton community genomics, genetics and breeding database being developed to enable basic, translational and applied research in cotton. It is being built using the open-source Tripal database infrastructure. CottonGen consolidates and expands the data from CottonDB and the Cotton Marker Database, providing enhanced tools for easy querying, visualizing and downloading research data.
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NONCODE is an integrated knowledge database dedicated to non-coding RNAs (excluding tRNAs and rRNAs). Now, there are 16 species in NONCODE(human, mouse, cow, rat, chicken, fruitfly, zebrafish, celegans, yeast, Arabidopsis, chimpanzee, gorilla, orangutan, rhesus macaque, opossum and platypus).The source of NONCODE includes literature and other public databases. We searched PubMed using key words ‘ncrna’, ‘noncoding’, ‘non-coding’,‘no code’, ‘non-code’, ‘lncrna’ or ‘lincrna. We retrieved the new identified lncRNAs and their annotation from the Supplementary Material or web site of these articles. Together with the newest data from Ensembl , RefSeq, lncRNAdb and GENCODE were processed through a standard pipeline for each species.
Database and knowledgebase of authenticated microbial genomics data with full data provenance to physical materials held within American Type Culture Collection's (ATCC) biorepository and culture collections. Data includes whole genome sequencing data for bacterial, viral and fungal strains at ATCC, their genome assemblies, metadata, drug susceptibility data, and more. All data is freely available for non-commercial research use only (RUO) applications via the web portal interface or via a REST-API. The goal is to provide the research community with provenance information and authentication between the biological source materials and reference genome assemblies derived from them.
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Thousands of circular RNAs (circRNAs) have recently been shown to be expressed in eukaryotic cells [Salzman et al. 2012, Jeck et al. 2013, Memczak et al. 2013, Salzman et al. 2013]. Here you can explore public circRNA datasets and download the custom python scripts needed to discover circRNAs in your own (ribominus) RNA-seq data.
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China’s digital forestry information platform was constructed according to the criteria and index system of forest sustainable management. the relative social, economic, and politic data was considered and collected, the database represents not only the current forestry development, but also the social, politic, and economic situations.
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Ecosounds is a repository of environmental audio recordings. This website facilitates the management, access, visualization, and analysis of environmental acoustic data. It uses the Acoustic Workbench software which is open source and available from GitHub. The website is run by the QUT Ecoacoustics Research Group to support bioacoustics and ecoacoustics research.