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The National Microbial Data Center (NMDC) is jointly constructed by the Institute of Microbiology of the Chinese Academy of Sciences (IMS), the Institute of Oceanography of the Chinese Academy of Sciences, the Institute of Infectious Diseases of the Chinese Center for Disease Control and Prevention, the Institute of Plant Physiology and Ecology of the Chinese Academy of Sciences, and the Computer Network Information Centre of the Chinese Academy of Sciences. The General Office of the Chinese Academy of Sciences is the parent department. The data resources covering the whole life cycle of microbiological research, including microbiological resources, microbiological and cross-technological methods, research processes and engineering, microbiomics, microbiological technologies, as well as microbiological literature, patents, experts and results. The Centre focuses on promoting the convergence and integration of scientific and technological resources in the field of microbiology to the national platform, strengthening the development, application and analysis of microbiological resources, enhancing the effective use of microbiological resources and the ability to support scientific and technological innovation, and providing high-quality scientific and technological resource sharing services for scientific research, technological progress and social development.
The IMPC is a confederation of international mouse phenotyping projects working towards the agreed goals of the consortium: To undertake the phenotyping of 20,000 mouse mutants over a ten year period, providing the first functional annotation of a mammalian genome. Maintain and expand a world-wide consortium of institutions with capacity and expertise to produce germ line transmission of targeted knockout mutations in embryonic stem cells for 20,000 known and predicted mouse genes. Test each mutant mouse line through a broad based primary phenotyping pipeline in all the major adult organ systems and most areas of major human disease. Through this activity and employing data annotation tools, systematically aim to discover and ascribe biological function to each gene, driving new ideas and underpinning future research into biological systems; Maintain and expand collaborative “networks” with specialist phenotyping consortia or laboratories, providing standardized secondary level phenotyping that enriches the primary dataset, and end-user, project specific tertiary level phenotyping that adds value to the mammalian gene functional annotation and fosters hypothesis driven research; and Provide a centralized data centre and portal for free, unrestricted access to primary and secondary data by the scientific community, promoting sharing of data, genotype-phenotype annotation, standard operating protocols, and the development of open source data analysis tools. Members of the IMPC may include research centers, funding organizations and corporations.