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Found 95 result(s)
The Intermediate Filament Database will function as a continuously updated review of the intermediate filament field and it is hoped that users will contribute to the development and expansion of the database on a regular basis. Contributions may include novel variants, new patients with previously discovered sequence and allelic variants. Suggestions on ways to improve the database are also welcome.
ChemSpider is a free chemical structure database providing fast access to over 58 million structures, properties and associated information. By integrating and linking compounds from more than 400 data sources, ChemSpider enables researchers to discover the most comprehensive view of freely available chemical data from a single online search. It is owned by the Royal Society of Chemistry. ChemSpider builds on the collected sources by adding additional properties, related information and links back to original data sources. ChemSpider offers text and structure searching to find compounds of interest and provides unique services to improve this data by curation and annotation and to integrate it with users’ applications.
Project Achilles is a systematic effort aimed at identifying and cataloging genetic vulnerabilities across hundreds of genomically characterized cancer cell lines. The project uses genome-wide genetic perturbation reagents (shRNAs or Cas9/sgRNAs) to silence or knock-out individual genes and identify those genes that affect cell survival. Large-scale functional screening of cancer cell lines provides a complementary approach to those studies that aim to characterize the molecular alterations (e.g. mutations, copy number alterations) of primary tumors, such as The Cancer Genome Atlas (TCGA). The overall goal of the project is to identify cancer genetic dependencies and link them to molecular characteristics in order to prioritize targets for therapeutic development and identify the patient population that might benefit from such targets. Project Achilles data is hosted on the Cancer Dependency Map Portal (DepMap) where it has been harmonized with our genomics and cellular models data. You can access the latest and all past datasets here: https://depmap.org/portal/download/all/
Xenbase's mission is to provide the international research community with a comprehensive, integrated and easy to use web based resource that gives access the diverse and rich genomic, expression and functional data available from Xenopus research. Xenbase also provides a critical data sharing infrastructure for many other NIH-funded projects, and is a focal point for the Xenopus community. In addition to our primary goal of supporting Xenopus researchers, Xenbase enhances the availability and visibility of Xenopus data to the broader biomedical research community.
Geochron is a global database that hosts geochronologic and thermochronologic information from detrital minerals. Information included with each sample consists of a table with the essential isotopic information and ages, a table with basic geologic metadata (e.g., location, collector, publication, etc.), a Pb/U Concordia diagram, and a relative age probability diagram. This information can be accessed and viewed with any web browser, and depending on the level of access desired, can be designated as either private or public. Loading information into Geochron requires the use of U-Pb_Redux, a Java-based program that also provides enhanced capabilities for data reduction, plotting, and analysis. Instructions are provided for three different levels of interaction with Geochron: 1. Accessing samples that are already in the Geochron database. 2. Preparation of information for new samples, and then transfer to Arizona LaserChron Center personnel for uploading to Geochron. 3. Preparation of information and uploading to Geochron using U-Pb_Redux.
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The National Microbial Data Center (NMDC) is jointly constructed by the Institute of Microbiology of the Chinese Academy of Sciences (IMS), the Institute of Oceanography of the Chinese Academy of Sciences, the Institute of Infectious Diseases of the Chinese Center for Disease Control and Prevention, the Institute of Plant Physiology and Ecology of the Chinese Academy of Sciences, and the Computer Network Information Centre of the Chinese Academy of Sciences. The General Office of the Chinese Academy of Sciences is the parent department. The data resources covering the whole life cycle of microbiological research, including microbiological resources, microbiological and cross-technological methods, research processes and engineering, microbiomics, microbiological technologies, as well as microbiological literature, patents, experts and results. The Centre focuses on promoting the convergence and integration of scientific and technological resources in the field of microbiology to the national platform, strengthening the development, application and analysis of microbiological resources, enhancing the effective use of microbiological resources and the ability to support scientific and technological innovation, and providing high-quality scientific and technological resource sharing services for scientific research, technological progress and social development.
The WorldWide Antimalarial Resistance Network (WWARN) is a collaborative platform generating innovative resources and reliable evidence to inform the malaria community on the factors affecting the efficacy of antimalarial medicines. Access to data is provided through diverse Tools and Resources: WWARN Explorer, Molecular Surveyor K13 Methodology, Molecular Surveyor pfmdr1 & pfcrt, Molecular Surveyor dhfr & dhps.
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Starting September 2013, MINT uses the IntAct database infrastructure to limit the duplication of efforts and to optimise future software development. Data manually curated by the MINT curators can now be accessed from the IntAct homepage at the EBI. Data maintenance and release, MINT PSICQUIC and IMEx services are under the responsibility of the IntAct team, while curation effort will be carried by both groups. The MINT development team now focuses on two new developments: mentha that integrates protein interaction information curated by IMEx databases and SIGNOR a database of logic relationships between human proteins. MINT is a public repository for molecular interactions reported in peer-reviewed journals.IT is a collection of molecular interaction databases that can be used to search for, analyze and graphically display molecular interaction networks and pathways from a wide variety of species. MINT is comprised of separate database components. HomoMINT, is an inferred human protein interatction database. Domino, is database of domain peptide interactions. A new component has been added called VirusMINT that explores the interactions of viral proteins with human proteins.
Remote Sensing Systems is a world leader in processing and analyzing microwave data from satellite microwave sensors. We specialize in algorithm development, instrument calibration, ocean product development, and product validation. We have worked with more than 30 satellite microwave radiometer, sounder, and scatterometer instruments over the past 40 years. Currently, we operationally produce satellite retrievals for SSMIS, AMSR2, WindSat, and ASCAT. The geophysical retrievals obtained from these sensors are made available in near-real-time (NRT) to the global scientific community and general public via FTP and this web site.
The PRIDE PRoteomics IDEntifications database is a centralized, standards compliant, public data repository for proteomics data, including protein and peptide identifications, post-translational modifications and supporting spectral evidence. PRIDE encourages and welcomes direct user submissions of mass spectrometry data to be published in peer-reviewed publications.
The central mission of the NACJD is to facilitate and encourage research in the criminal justice field by sharing data resources. Specific goals include providing computer-readable data for the quantitative study of crime and the criminal justice system through the development of a central data archive, supplying technical assistance in the selection of data collections and computer hardware and software for data analysis, and training in quantitative methods of social science research to facilitate secondary analysis of criminal justice data
The Language Archive at the Max Planck Institute in Nijmegen provides a unique record of how people around the world use language in everyday life. It focuses on collecting spoken and signed language materials in audio and video form along with transcriptions, analyses, annotations and other types of relevant material (e.g. photos, accompanying notes).
The US Virtual Astronomical Observatory (VAO) is the VO effort based in the US, and it is one of many VO projects currently underway worldwide. The primary emphasis of the VAO is to provide new scientific research capabilities to the astronomy community. Thus an essential component of the VAO activity is obtaining input from US astronomers about the research tools that are most urgently needed in their work, and this information will guide the development efforts of the VAO. >>>!!!<<< Funding discontinued in 2014 and all software, documentation, and other digital assets developed under the VAO are stored in the VAO Project Repository https://sites.google.com/site/usvirtualobservatory/ . Code is archived on Github https://github.com/TomMcGlynn/usvirtualobservatory . >>>!!!<<<
IntAct provides a freely available, open source database system and analysis tools for molecular interaction data. All interactions are derived from literature curation or direct user submissions and are freely available.
UNC Dataverse is an open-source repository software application for archiving, sharing, and accessing research data of all kinds. Each dataverse within the larger repository contains a multitude of datasets, and each dataset contains descriptive metadata and data files. UNC Dataverse is hosted by Odum Institute for Research in Social Science.
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SAFER-Data is a web-based interface to the Environmental Data Archive maintained by the Environmental Research Centre (ERC) in the Environmental Protection Agency (EPA) of Ireland, who has responsibilities for a wide range of licensing, enforcement, monitoring and assessment activities associated with environmental protection.
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EarthByte is an internationally leading eGeoscience collaboration between several Australian Universities, international centres of excellence and industry partners. One of the fundamental aims of the EarthByte Group is geodata synthesis through space and time, assimilating the wealth of disparate geological and geophysical data into a four-dimensional Earth model including tectonics, geodynamics and surface processes. The EarthByte Group is pursuing open innovation via collaborative software development, high performance and distributed computing, “big data” analysis and by making open access digital data collections available to the community.
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KEGG is a database resource for understanding high-level functions and utilities of the biological system, such as the cell, the organism and the ecosystem, from molecular-level information, especially large-scale molecular datasets generated by genome sequencing and other high-throughput experimental technologies
Measurements Of Pollution In The Troposphere (MOPITT) was launched into sun-synchronous polar orbit on December 18, 1999, aboard TERRA, a NASA satellite orbiting 705 km above the Earth. MOPITT monitors changes in pollution patterns and the effects on Earth’s troposphere. MOPITT uses near-infrared radiation at 2.3 µm and thermal-infrared radiation at 4.7 µm to calculate atmospheric profiles of CO.
VIPERdb is a database for icosahedral virus capsid structures . The emphasis of the resource is on providing data from structural and computational analyses on these systems, as well as high quality renderings for visual exploration. In addition, all virus capsids are placed in a single icosahedral orientation convention, facilitating comparison between different structures. The web site includes powerful search utilities , links to other relevant databases, background information on virus capsid structure, and useful database interface tools.
The Cancer Cell Line Encyclopedia project is a collaboration between the Broad Institute, and the Novartis Institutes for Biomedical Research and its Genomics Institute of the Novartis Research Foundation to conduct a detailed genetic and pharmacologic characterization of a large panel of human cancer models, to develop integrated computational analyses that link distinct pharmacologic vulnerabilities to genomic patterns and to translate cell line integrative genomics into cancer patient stratification. The CCLE provides public access to genomic data, analysis and visualization for about 1000 cell lines.