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Found 376 result(s)

Project Achilles

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Project Achilles is a systematic effort aimed at identifying and cataloging genetic vulnerabilities across hundreds of genomically characterized cancer cell lines. The project uses genome-wide genetic perturbation reagents (shRNAs or Cas9/sgRNAs) to silence or knock-out individual genes and identify those genes that affect cell survival. Large-scale functional screening of cancer cell lines provides a complementary approach to those studies that aim to characterize the molecular alterations (e.g. mutations, copy number alterations) of primary tumors, such as The Cancer Genome Atlas (TCGA). The overall goal of the project is to identify cancer genetic dependencies and link them to molecular characteristics in order to prioritize targets for therapeutic development and identify the patient population that might benefit from such targets. Project Achilles data is hosted on the Cancer Dependency Map Portal (DepMap) where it has been harmonized with our genomics and cellular models data. You can access the latest and all past datasets here: https://depmap.org/portal/download/all/

Universal PBM Resource for Oligonucleotide Binding Evaluation

UniPROBE

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The UniPROBE (Universal PBM Resource for Oligonucleotide Binding Evaluation) database hosts data generated by universal protein binding microarray (PBM) technology on the in vitro DNA binding specificities of proteins. This initial release of the UniPROBE database provides a centralized resource for accessing comprehensive data on the preferences of proteins for all possible sequence variants ('words') of length k ('k-mers'), as well as position weight matrix (PWM) and graphical sequence logo representations of the k-mer data. In total, the database currently hosts DNA binding data for 406 nonredundant proteins from a diverse collection of organisms, including the prokaryote Vibrio harveyi, the eukaryotic malarial parasite Plasmodium falciparum, the parasitic Apicomplexan Cryptosporidium parvum, the yeast Saccharomyces cerevisiae, the worm Caenorhabditis elegans, mouse, and human. The database's web tools (on the right) include a text-based search, a function for assessing motif similarity between user-entered data and database PWMs, and a function for locating putative binding sites along user-entered nucleotide sequences

Tropical Cyclone Information System

JPL Tropical Cyclone Information System

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The JPL Tropical Cyclone Information System (TCIS) was developed to support hurricane research. There are three components to TCIS; a global archive of multi-satellite hurricane observations 1999-2010 (Tropical Cyclone Data Archive), North Atlantic Hurricane Watch and ASA Convective Processes Experiment (CPEX) aircraft campaign. Together, data and visualizations from the real time system and data archive can be used to study hurricane process, validate and improve models, and assist in developing new algorithms and data assimilation techniques.

Center for Demography of Health and Aging

CDHA

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The CDHA assists researchers to create, document, and distribute public use microdata on health and aging for secondary analysis. Major research themes include: midlife development and aging; economics of population aging; inequalities in health and aging; international comparative studies of health and aging; and the investigation of linkages between social-demographic and biomedical research in population aging. The CDHA is one of fourteen demography centers on aging sponsored by the National Institute on Aging.

Integrated Fertility Survey Series

IFSS

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>>>>>> !!! <<<<<< This website ceased operation on Sept. 30, 2020, as the website is no longer funded >>>>> !!!!! <<<<

National Archive of Criminal Justice Data

NACJD

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The central mission of the NACJD is to facilitate and encourage research in the criminal justice field by sharing data resources. Specific goals include providing computer-readable data for the quantitative study of crime and the criminal justice system through the development of a central data archive, supplying technical assistance in the selection of data collections and computer hardware and software for data analysis, and training in quantitative methods of social science research to facilitate secondary analysis of criminal justice data

Analysis of the Interstellar Medium of Isolated Galaxies

AMIGA

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The AMIGA project (Analysis of the interstellar Medium of Isolated GAlaxies) involves the identification and study of a statistically significant sample of the most isolated galaxies in the local Universe. Our goal is to quantify the properties of different phases of the interstellar medium in these galaxies which are likely to be least affected by their external environment.

London Datastore

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The London Datastore is an initiative by the Greater London Authority (GLA) to release as much of the data that it holds as possible.

West of Scotland Twenty-07 Study

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The Twenty-07 Study was set up in 1986 in order to investigate the reasons for differences in health by socio-economic circumstances, gender, area of residence, age, ethnic group, and family type. 4510 people are being followed for 20 years. The initial wave of data collection took place in 1987/8, when respondents were aged 15, 35 and 55. The final wave of data collection took place in 2007/08 when respondents were aged 35, 55 and 75. In this way the Twenty-07 Study provides us with unique opportunities to investigate both the changes in people's lives over 20 years and how they affect their health, and the differences in people's experiences at the same ages 20 years apart, and how these have different effects on their health.

Nothobranchius furzeri Information Network

NFIN

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The species Nothobranchius furzeri possesses several characteristics which make it a particularly attractive model system for age research: Inbred line GRZ shows a captive lifespan of only three months. There is large variation in life-history traits between different isolates. Lifespan can be prolonged by environmental manipulations and drugs. The aim of this website is to provide information on N. furzeri and to foster the development of a group of interest which aims at creating a consortium to establish this organism as a model for developmental and age research.

Reality Commons

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Cell phones have become an important platform for the understanding of social dynamics and influence, because of their pervasiveness, sensing capabilities, and computational power. Many applications have emerged in recent years in mobile health, mobile banking, location based services, media democracy, and social movements. With these new capabilities, we can potentially be able to identify exact points and times of infection for diseases, determine who most influences us to gain weight or become healthier, know exactly how information flows among employees and productivity emerges in our work spaces, and understand how rumors spread. In an attempt to address these challenges, we release several mobile data sets here in "Reality Commons" that contain the dynamics of several communities of about 100 people each. We invite researchers to propose and submit their own applications of the data to demonstrate the scientific and business values of these data sets, suggest how to meaningfully extend these experiments to larger populations, and develop the math that fits agent-based models or systems dynamics models to larger populations. These data sets were collected with tools developed in the MIT Human Dynamics Lab and are now available as open source projects or at cost.

ILL Data Portal

Institut Laue-Langevin Data Portal

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In order to control access to the experimental data obtained at the ILL in a coherent and secure fashion, the ILL has recently developed a single portal for consulting, downloading and managing your data. Here “data” is understood to mean raw data (i.e. numor files), processed data, and meta-data (e.g. log files or “logs”).

Cancer Genome Anatomy Project

CGAP

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>>>!!!<<< Noticed 26.08.2020: The NCI CBIIT instance of the CGAP no longer exist on this website. The Mitelman Database of Chromosome Aberrations and Gene Fusions in Cancer has a new home at the NCI-funded Institute for Systems Biology Cancer Genomics Cloud available at the following location: https://mitelmandatabase.isb-cgc.org >>>!!!<<<

National Genomic Resources Repository

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National Genomic Resources Repository is established as an institutional framework for methodical and centralized efforts to collect, generate, conserve and distribute genomic resources for agricultural research.

Research Data On Gender Relations In Academia

CEWS Forschungsdaten

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Numerous studies on gender relations and gender equality policy in academia regularly produce research data that could be useful for a secondary analysis and for other research topics. At present, only a small amount of research data that was explicitly collected on gender relations in academia is archived. Long-term surveys such as graduate studies or social surveys on students are also available to be used in gender-specific studies. CEWS would like to support researchers in their search for research data and at the same time motivate them to archive data from their own projects and thus make them accessible to other researchers by providing search options at GESIS and other data-providing institutions as well as basic information on data archiving.

ArkeoGIS

ArkeoGIS

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ArkeoGIS is a unified scientific data publishing platform. It is a multilingual Geographic Information System (GIS), initially developed in order to mutualize archaeological and paleoenvironmental data of the Rhine Valley. Today, it allows the pooling of spatialized scientific data concerning the past, from prehistory to the present day. The databases come from the work of institutional researchers, doctoral students, master students, private companies and archaeological services. They are stored on the TGIR Huma-Num service grid and archived as part of the Huma-Num/CINES long-term archiving service. Because of their sensitive nature, which could lead to the looting of archaeological deposits, access to the tool is reserved to archaeological professionals, from research institutions or non-profit organizations. Each user can query online all or part of the available databases and export the results of his query to other tools.

Edinburgh DataShare

DataShare

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Edinburgh DataShare is a digital repository of research data produced at the University of Edinburgh, hosted by the Research Data Service in Information Services. Edinburgh University researchers who have produced research data associated with an existing or forthcoming publication, or which has potential use for other researchers, are invited to upload their dataset for sharing and safekeeping. A persistent identifier and suggested citation will be provided.

The Plastics-Active Enzymes Database

PAZy

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Plastics are widely used in our economy and each year, at least 350-400 million tons are being produced at a global level. Due to poor recycling and low circular use, tens of millions of tons accumulate annually in marine and terrestrial environments. While it has become obvious that micro and macroplastics contaminate our environments recent research has identified few bacteria and fungi actively degrading plastics by enzymatic reactions. In general these are promiscuous enzymes (hydrolases) acting on low crystaline and mostly low density polymers of PET, ester-based PUR and oligomers of PA. Notably today, no enzymes have been characterized on a biochemical level for polymeric and crystaline PE, ether-based PUR, PS, PVC, PP. While many publications report on plastic degradation often, no convincing biochemical data have been published. Therefore the PAZy database lists exclusively biochemically characterized plastic-active enzymes. Predicted and putative enzymes that were not characterized on a biochemical, functional or structural level are not included in the PAZy database. The entries are manually curated.

MIDAS

Nacionalinis atviros prieigos mokslinių tyrimų duomenų archyvas

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MIDAS is a national research data repository. The aim of MIDAS is to collect, process, store and analyse research data and other relevant information in all fields of knowledge, enabling free, easy and convenient access to the data via the Internet. MIDAS provides services for registered and unregistered users: students, listeners, academics, researchers, scientists, research administrators, other actors of the research and studies ecosystem, and all individuals interested in research data. MIDAS consists of the MIDAS portal and MIDAS user account. The MIDAS portal is a public space accessible to anyone interested in discovering and viewing published research Data and their metadata, whereas MIDAS user account is available to registered users only. MIDAS is managed by Vilnius University.

GESIS Data Archive

GESIS Long-term digital preservation

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GESIS preserves (mainly quantitative) social research data to make it available to the scientific research community. The data is described in a standardized way, secured for the long term, provided with a permanent identifier (DOI), and can be easily found and reused through browser-optimized catalogs (https://search.gesis.org/).

Canadian Open Neuroscience Platform Portal

CONP

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The CONP portal is a web interface for the Canadian Open Neuroscience Platform (CONP) to facilitate open science in the neuroscience community. CONP simplifies global researcher access and sharing of datasets and tools. The portal internalizes the cycle of a typical research project: starting with data acquisition, followed by processing using already existing/published tools, and ultimately publication of the obtained results including a link to the original dataset. From more information on CONP, please visit https://conp.ca

Speech and Language Data Repository

SLDR

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>>>>>!!!<<<<< As of 01/12/2015, deposit of data on SLDR website will be suspended to allow the public opening of Ortolang platform https://www.ortolang.fr/#/market/home .>>>>>!!!<<<<<

Research Data Center PIAAC at GESIS

RDC PIAAC

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The Research Data Center PIAAC (RDC PIAAC) has been accredited by the German Data Forum (RatSWD). The RDC PIAAC makes research data accessible to the scientific community and offers advice to the users. The RDC PIAAC provides German and international datasets in the educational field focusing on the adult population, especially on the Programme for the International Assessment of Adult Competencies (PIAAC).

Nordicana D

Nordicana D collection

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Nordicana series D is a formatted, online data report series archived at CEN. It is produced only in electronic form and is freely and openly accessible to CEN researchers and to other users. Each issue is published in French and in English, and is indexed via an assigned digital object identifier (DOI). An issue may be updated, for example with new data, as a new version number, but will retain the same DOI. Each issue contains data sets and extensive metadata that explain the origin of the data, the format of the data, the history of updates via different version numbers, and the format that should be adopted to cite the data.

Collaborative Psychiatric Epidemiology Surveys 2001 - 2003

CPES

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CPES provides access to information that relates to mental disorders among the general population. Its primary goal is to collect data about the prevalence of mental disorders and their treatments in adult populations in the United States. It also allows for research related to cultural and ethnic influences on mental health. CPES combines the data collected in three different nationally representative surveys (National Comorbidity Survey Replication, National Survey of American Life, National Latino and Asian American Study).